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Novel nonnucleoside inhibitor of hepatitis C virus RNA-dependent RNA polymerase.
Howe AY, Bloom J, Baldick CJ, Benetatos CA, Cheng H, Christensen JS, Chunduru SK, Coburn GA, Feld B, Gopalsamy A, Gorczyca WP, Herrmann S, Johann S, Jiang X, Kimberland ML, Krisnamurthy G, Olson M, Orlowski M, Swanberg S, Thompson I, Thorn M, Del Vecchio A, Young DC, van Zeijl M, Ellingboe JW, Upeslacis J, Collett M, Mansour TS, O'Connell JF. Howe AY, et al. Among authors: chunduru sk. Antimicrob Agents Chemother. 2004 Dec;48(12):4813-21. doi: 10.1128/AAC.48.12.4813-4821.2004. Antimicrob Agents Chemother. 2004. PMID: 15561861 Free PMC article.
The discovery of pyrano[3,4-b]indole-based allosteric inhibitors of HCV NS5B polymerase with in vivo activity.
Laporte MG, Jackson RW, Draper TL, Gaboury JA, Galie K, Herbertz T, Hussey AR, Rippin SR, Benetatos CA, Chunduru SK, Christensen JS, Coburn GA, Rizzo CJ, Rhodes G, O'Connell J, Howe AY, Mansour TS, Collett MS, Pevear DC, Young DC, Gao T, Tyrrell DL, Kneteman NM, Burns CJ, Condon SM. Laporte MG, et al. Among authors: chunduru sk. ChemMedChem. 2008 Oct;3(10):1508-15. doi: 10.1002/cmdc.200800168. ChemMedChem. 2008. PMID: 18729128 No abstract available.
The discovery and structure-activity relationships of pyrano[3,4-b]indole based inhibitors of hepatitis C virus NS5B polymerase.
LaPorte MG, Draper TL, Miller LE, Blackledge CW, Leister LK, Amparo E, Hussey AR, Young DC, Chunduru SK, Benetatos CA, Rhodes G, Gopalsamy A, Herbertz T, Burns CJ, Condon SM. LaPorte MG, et al. Among authors: chunduru sk. Bioorg Med Chem Lett. 2010 May 1;20(9):2968-73. doi: 10.1016/j.bmcl.2010.03.002. Epub 2010 Mar 6. Bioorg Med Chem Lett. 2010. PMID: 20347591
Mechanism of action of a pestivirus antiviral compound.
Baginski SG, Pevear DC, Seipel M, Sun SC, Benetatos CA, Chunduru SK, Rice CM, Collett MS. Baginski SG, et al. Among authors: chunduru sk. Proc Natl Acad Sci U S A. 2000 Jul 5;97(14):7981-6. doi: 10.1073/pnas.140220397. Proc Natl Acad Sci U S A. 2000. PMID: 10869440 Free PMC article.
Tetrahydrobenzothiophene inhibitors of hepatitis C virus NS5B polymerase.
Laporte MG, Lessen TA, Leister L, Cebzanov D, Amparo E, Faust C, Ortlip D, Bailey TR, Nitz TJ, Chunduru SK, Young DC, Burns CJ. Laporte MG, et al. Among authors: chunduru sk. Bioorg Med Chem Lett. 2006 Jan 1;16(1):100-3. doi: 10.1016/j.bmcl.2005.09.047. Epub 2005 Nov 2. Bioorg Med Chem Lett. 2006. PMID: 16260131
35 results