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Programmable C-to-U RNA editing using the human APOBEC3A deaminase.
Huang X, Lv J, Li Y, Mao S, Li Z, Jing Z, Sun Y, Zhang X, Shen S, Wang X, Di M, Ge J, Huang X, Zuo E, Chi T. Huang X, et al. Among authors: chi t. EMBO J. 2020 Nov 16;39(22):e104741. doi: 10.15252/embj.2020104741. Epub 2020 Oct 15. EMBO J. 2020. PMID: 33058229 Free PMC article.
REPAIRx, a specific yet highly efficient programmable A > I RNA base editor.
Liu Y, Mao S, Huang S, Li Y, Chen Y, Di M, Huang X, Lv J, Wang X, Ge J, Shen S, Zhang X, Liu D, Huang X, Chi T. Liu Y, et al. Among authors: chi t. EMBO J. 2020 Nov 16;39(22):e104748. doi: 10.15252/embj.2020104748. Epub 2020 Oct 15. EMBO J. 2020. PMID: 33058207 Free PMC article.
Enhancing prime editing by Csy4-mediated processing of pegRNA.
Liu Y, Yang G, Huang S, Li X, Wang X, Li G, Chi T, Chen Y, Huang X, Wang X. Liu Y, et al. Among authors: chi t. Cell Res. 2021 Oct;31(10):1134-1136. doi: 10.1038/s41422-021-00520-x. Epub 2021 Jun 8. Cell Res. 2021. PMID: 34103663 Free PMC article. No abstract available.
Large-scale multiplexed mosaic CRISPR perturbation in the whole organism.
Liu B, Jing Z, Zhang X, Chen Y, Mao S, Kaundal R, Zou Y, Wei G, Zang Y, Wang X, Lin W, Di M, Sun Y, Chen Q, Li Y, Xia J, Sun J, Lin CP, Huang X, Chi T. Liu B, et al. Among authors: chi t. Cell. 2022 Aug 4;185(16):3008-3024.e16. doi: 10.1016/j.cell.2022.06.039. Epub 2022 Jul 22. Cell. 2022. PMID: 35870449 Free article.
581 results