Chene P - Search Results

1

Structural States of Hdm2 and HdmX: X-ray Elucidation of Adaptations and Binding Interactions for Different Chemical Compound Classes.

Kallen J, Izaac A, Chau S, Wirth E, Schoepfer J, Mah R, Schlapbach A, Stutz S, Vaupel A, Guagnano V, Masuya K, Stachyra TM, Salem B, Chene P, Gessier F, Holzer P, Furet P. Kallen J, et al. Among authors: chene p. ChemMedChem. 2019 Jul 17;14(14):1305-1314. doi: 10.1002/cmdc.201900201. Epub 2019 May 27. ChemMedChem. 2019. PMID: 31066983

2

Dual specificity of Src homology 2 domains for phosphotyrosine peptide ligands.

Gay B, Furet P, García-Echeverría C, Rahuel J, Chène P, Fretz H, Schoepfer J, Caravatti G. Gay B, et al. Among authors: chene p. Biochemistry. 1997 May 13;36(19):5712-8. doi: 10.1021/bi962642y. Biochemistry. 1997. PMID: 9153411

3

A small synthetic peptide, which inhibits the p53-hdm2 interaction, stimulates the p53 pathway in tumour cell lines.

Chène P, Fuchs J, Bohn J, García-Echeverría C, Furet P, Fabbro D. Chène P, et al. J Mol Biol. 2000 May 26;299(1):245-53. doi: 10.1006/jmbi.2000.3738. J Mol Biol. 2000. PMID: 10860736

4

Discovery of potent antagonists of the interaction between human double minute 2 and tumor suppressor p53.

García-Echeverría C, Chène P, Blommers MJ, Furet P. García-Echeverría C, et al. Among authors: chene p. J Med Chem. 2000 Aug 24;43(17):3205-8. doi: 10.1021/jm990966p. J Med Chem. 2000. PMID: 10966738 No abstract available.

5

Coupling of the antennapedia third helix to a potent antagonist of the p53/hdm2 protein-protein interaction.

García-Echeverría C, Furet P, Chène P. García-Echeverría C, et al. Among authors: chene p. Bioorg Med Chem Lett. 2001 Aug 20;11(16):2161-4. doi: 10.1016/s0960-894x(01)00394-8. Bioorg Med Chem Lett. 2001. PMID: 11514160

6

Study of the cytotoxic effect of a peptidic inhibitor of the p53-hdm2 interaction in tumor cells.

Chène P, Fuchs J, Carena I, Furet P, García-Echeverría C. Chène P, et al. FEBS Lett. 2002 Oct 9;529(2-3):293-7. doi: 10.1016/s0014-5793(02)03362-8. FEBS Lett. 2002. PMID: 12372616 Free article.

7

Inhibition of the p53-hdm2 interaction with low molecular weight compounds.

Chène P. Chène P. Cell Cycle. 2004 Apr;3(4):460-1. doi: 10.4161/cc.3.4.791. Epub 2004 Apr 1. Cell Cycle. 2004. PMID: 14976429

8

Development and implementation of a highly miniaturized confocal 2D-FIDA-based high-throughput screening assay to search for active site modulators of the human heat shock protein 90beta.

Schilb A, Riou V, Schoepfer J, Ottl J, Müller K, Chene P, Mayr LM, Filipuzzi I. Schilb A, et al. Among authors: chene p. J Biomol Screen. 2004 Oct;9(7):569-77. doi: 10.1177/1087057104265538. J Biomol Screen. 2004. PMID: 15475476

9

Inhibition of DNA helicases with DNA-competitive inhibitors.

Dubaele S, Jahnke W, Schoepfer J, Fuchs J, Chène P. Dubaele S, et al. Among authors: chene p. Bioorg Med Chem Lett. 2006 Feb 15;16(4):923-7. doi: 10.1016/j.bmcl.2005.10.110. Epub 2005 Nov 21. Bioorg Med Chem Lett. 2006. PMID: 16300943

10

Drugs targeting protein-protein interactions.

Chène P. Chène P. ChemMedChem. 2006 Apr;1(4):400-11. doi: 10.1002/cmdc.200600004. ChemMedChem. 2006. PMID: 16892375 Review.

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