Chen Y - Search Results

1

Histone phosphorylation integrates the hepatic glucagon-PKA-CREB gluconeogenesis program in response to fasting.

Zhao Y, Li S, Chen Y, Wang Y, Wei Y, Zhou T, Zhang Y, Yang Y, Chen L, Liu Y, Hu C, Zhou B, Ding Q. Zhao Y, et al. Among authors: chen l, chen y. Mol Cell. 2023 Apr 6;83(7):1093-1108.e8. doi: 10.1016/j.molcel.2023.02.007. Epub 2023 Mar 1. Mol Cell. 2023. PMID: 36863348 Free article.

2

A Self-restricted CRISPR System to Reduce Off-target Effects.

Chen Y, Liu X, Zhang Y, Wang H, Ying H, Liu M, Li D, Lui KO, Ding Q. Chen Y, et al. Mol Ther. 2016 Sep;24(9):1508-10. doi: 10.1038/mt.2016.172. Mol Ther. 2016. PMID: 27687135 Free PMC article. No abstract available.

3

CRISPR/Cas9 with single guide RNA expression driven by small tRNA promoters showed reduced editing efficiency compared to a U6 promoter.

Wei Y, Qiu Y, Chen Y, Liu G, Zhang Y, Xu L, Ding Q. Wei Y, et al. Among authors: chen y. RNA. 2017 Jan;23(1):1-5. doi: 10.1261/rna.057596.116. Epub 2016 Oct 14. RNA. 2017. PMID: 27742910 Free PMC article.

4

Prevention of Muscle Wasting by CRISPR/Cas9-mediated Disruption of Myostatin In Vivo.

Wei Y, Chen Y, Qiu Y, Zhao H, Liu G, Zhang Y, Meng Q, Wu G, Chen Y, Cai X, Wang H, Ying H, Zhou B, Liu M, Li D, Ding Q. Wei Y, et al. Among authors: chen y. Mol Ther. 2016 Nov;24(11):1889-1891. doi: 10.1038/mt.2016.192. Mol Ther. 2016. PMID: 27916995 Free PMC article. No abstract available.

5

Applications of genome editing tools in precision medicine research.

Li S, Yang YY, Qiu Y, Chen Y, Xu LW, Ding QR. Li S, et al. Among authors: chen y. Yi Chuan. 2017 Mar 20;39(3):177-188. doi: 10.16288/j.yczz.16-395. Yi Chuan. 2017. PMID: 28420614 Review.

6

Genetic and Chemical Screenings Identify HDAC3 as a Key Regulator in Hepatic Differentiation of Human Pluripotent Stem Cells.

Li S, Li M, Liu X, Yang Y, Wei Y, Chen Y, Qiu Y, Zhou T, Feng Z, Ma D, Fang J, Ying H, Wang H, Musunuru K, Shao Z, Zhao Y, Ding Q. Li S, et al. Among authors: chen y. Stem Cell Reports. 2018 Jul 10;11(1):22-31. doi: 10.1016/j.stemcr.2018.05.001. Epub 2018 May 31. Stem Cell Reports. 2018. PMID: 29861165 Free PMC article.

7

Genetic Modulation of RNA Splicing with a CRISPR-Guided Cytidine Deaminase.

Yuan J, Ma Y, Huang T, Chen Y, Peng Y, Li B, Li J, Zhang Y, Song B, Sun X, Ding Q, Song Y, Chang X. Yuan J, et al. Among authors: chen y. Mol Cell. 2018 Oct 18;72(2):380-394.e7. doi: 10.1016/j.molcel.2018.09.002. Epub 2018 Oct 4. Mol Cell. 2018. PMID: 30293782 Free article.

8

Screening of FDA-approved drugs identifies sutent as a modulator of UCP1 expression in brown adipose tissue.

Qiu Y, Sun Y, Xu D, Yang Y, Liu X, Wei Y, Chen Y, Feng Z, Li S, Reyad-Ul Ferdous M, Zhao Y, Xu H, Lao Y, Ding Q. Qiu Y, et al. Among authors: chen y. EBioMedicine. 2018 Nov;37:344-355. doi: 10.1016/j.ebiom.2018.10.019. Epub 2018 Oct 20. EBioMedicine. 2018. PMID: 30348622 Free PMC article.

9

Gain-of-Function Mutations of SLC16A11 Contribute to the Pathogenesis of Type 2 Diabetes.

Zhao Y, Feng Z, Zhang Y, Sun Y, Chen Y, Liu X, Li S, Zhou T, Chen L, Wei Y, Ma D, Lui KO, Ying H, Chen Y, Ding Q. Zhao Y, et al. Among authors: chen l, chen y. Cell Rep. 2019 Jan 22;26(4):884-892.e4. doi: 10.1016/j.celrep.2018.12.100. Cell Rep. 2019. PMID: 30673611 Free article.

10

Genome-scale CRISPR screening for potential targets of ginsenoside compound K.

Yang Y, Liu X, Li S, Chen Y, Zhao Y, Wei Y, Qiu Y, Liu Y, Zhou Z, Han J, Wu G, Ding Q. Yang Y, et al. Among authors: chen y. Cell Death Dis. 2020 Jan 20;11(1):39. doi: 10.1038/s41419-020-2234-5. Cell Death Dis. 2020. PMID: 31959745 Free PMC article.

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