Chen X - Search Results

1

Lactate dehydrogenase D is a general dehydrogenase for D-2-hydroxyacids and is associated with D-lactic acidosis.

Jin S, Chen X, Yang J, Ding J. Jin S, et al. Among authors: chen x. Nat Commun. 2023 Oct 20;14(1):6638. doi: 10.1038/s41467-023-42456-3. Nat Commun. 2023. PMID: 37863926 Free PMC article.

2

Neutralization mechanism of a human antibody with pan-coronavirus reactivity including SARS-CoV-2.

Sun X, Yi C, Zhu Y, Ding L, Xia S, Chen X, Liu M, Gu C, Lu X, Fu Y, Chen S, Zhang T, Zhang Y, Yang Z, Ma L, Gu W, Hu G, Du S, Yan R, Fu W, Yuan S, Qiu C, Zhao C, Zhang X, He Y, Qu A, Zhou X, Li X, Wong G, Deng Q, Zhou Q, Lu H, Ling Z, Ding J, Lu L, Xu J, Xie Y, Sun B. Sun X, et al. Among authors: chen s, chen x. Nat Microbiol. 2022 Jul;7(7):1063-1074. doi: 10.1038/s41564-022-01155-3. Epub 2022 Jun 30. Nat Microbiol. 2022. PMID: 35773398

3

Structures of a constitutively active mutant of human IDH3 reveal new insights into the mechanisms of allosteric activation and the catalytic reaction.

Chen X, Sun P, Liu Y, Shen S, Ma T, Ding J. Chen X, et al. J Biol Chem. 2022 Dec;298(12):102695. doi: 10.1016/j.jbc.2022.102695. Epub 2022 Nov 12. J Biol Chem. 2022. PMID: 36375638 Free PMC article.

4

Molecular insights into the catalysis and regulation of mammalian NAD-dependent isocitrate dehydrogenases.

Chen X, Ding J. Chen X, et al. Curr Opin Struct Biol. 2023 Oct;82:102672. doi: 10.1016/j.sbi.2023.102672. Epub 2023 Aug 3. Curr Opin Struct Biol. 2023. PMID: 37542909 Free article. Review.

5

Structure and biochemical characterization of l-2-hydroxyglutarate dehydrogenase and its role in the pathogenesis of l-2-hydroxyglutaric aciduria.

Yang J, Chen X, Jin S, Ding J. Yang J, et al. Among authors: chen x. J Biol Chem. 2024 Jan;300(1):105491. doi: 10.1016/j.jbc.2023.105491. Epub 2023 Nov 22. J Biol Chem. 2024. PMID: 37995940 Free PMC article.

6

Discrimination of Methionine Sulfoxide and Sulfone by Human Neutrophil Elastase.

Leahy D, Grant C, Jackson A, Duff A, Tardiota N, Van Haeften J, Chen X, Peake JM, Kruppa MD, Smith ET, Johnson DA, Lott WB, Harris JM. Leahy D, et al. Among authors: chen x. Molecules. 2021 Sep 2;26(17):5344. doi: 10.3390/molecules26175344. Molecules. 2021. PMID: 34500777 Free PMC article.

7

Potent, multi-target serine protease inhibition achieved by a simplified β-sheet motif.

Chen X, Riley BT, de Veer SJ, Hoke DE, Van Haeften J, Leahy D, Swedberg JE, Brattsand M, Hartfield PJ, Buckle AM, Harris JM. Chen X, et al. PLoS One. 2019 Jan 22;14(1):e0210842. doi: 10.1371/journal.pone.0210842. eCollection 2019. PLoS One. 2019. PMID: 30668585 Free PMC article.

8

Screening and separation of natural anticancer active ingredients related to phospholipase C.

Liu N, Yue Z, Hu S, Xing R, Wang R, Yang L, Chen X. Liu N, et al. Among authors: chen x. J Sep Sci. 2024 May;47(9-10):e2300898. doi: 10.1002/jssc.202300898. J Sep Sci. 2024. PMID: 38726747

9

Extracellular adenosine triphosphate skews the T helper cell balance and enhances neutrophil activation in mice with food allergies.

Zhang X, Chen X, Yang F, Shao H, Bai T, Meng X, Wu Y, Yang A, Chen H, Li X. Zhang X, et al. Among authors: chen x. Food Funct. 2024 May 10. doi: 10.1039/d4fo01135j. Online ahead of print. Food Funct. 2024. PMID: 38726659

10

Rational Design and Pharmacomodulation of ¹⁸F-Labeled Biotin/FAPI-Conjugated Heterodimers.

Chen X, Xia D, Zeng X, Meng L, Wang Y, Li H, Zhang J, Zhao Z, Zhuang R, Fang J, Zhang X, Guo Z. Chen X, et al. J Med Chem. 2024 May 10. doi: 10.1021/acs.jmedchem.4c00544. Online ahead of print. J Med Chem. 2024. PMID: 38726551

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