Chen MH - Search Results

1

Synthesis and biological activity of 2H-quinolizin-2-one based p38alpha MAP kinase inhibitors.

Tynebor RM, Chen MH, Natarajan SR, O'Neill EA, Thompson JE, Fitzgerald CE, O'Keefe SJ, Doherty JB. Tynebor RM, et al. Among authors: chen mh. Bioorg Med Chem Lett. 2010 May 1;20(9):2765-9. doi: 10.1016/j.bmcl.2010.03.069. Epub 2010 Mar 21. Bioorg Med Chem Lett. 2010. PMID: 20378346

2

SAR of 3,4-dihydropyrido[3,2-d]pyrimidone p38 inhibitors.

Liu L, Stelmach JE, Natarajan SR, Chen MH, Singh SB, Schwartz CD, Fitzgerald CE, O'Keefe SJ, Zaller DM, Schmatz DM, Doherty JB. Liu L, et al. Among authors: chen mh. Bioorg Med Chem Lett. 2003 Nov 17;13(22):3979-82. doi: 10.1016/j.bmcl.2003.08.059. Bioorg Med Chem Lett. 2003. PMID: 14592489

3

Synthesis and biological activity of quinolinone and dihydroquinolinone p38 MAP kinase inhibitors.

Chen MH, Fitzgerald P, Singh SB, O'Neill EA, Schwartz CD, Thompson CM, O'Keefe SJ, Zaller DM, Doherty JB. Chen MH, et al. Bioorg Med Chem Lett. 2008 Mar 15;18(6):2222-6. doi: 10.1016/j.bmcl.2006.10.097. Epub 2006 Nov 6. Bioorg Med Chem Lett. 2008. PMID: 18316187

4

Synthesis and biological activity of pyridopyridazin-6-one p38 MAP kinase inhibitors. Part 1.

Tynebor RM, Chen MH, Natarajan SR, O'Neill EA, Thompson JE, Fitzgerald CE, O'Keefe SJ, Doherty JB. Tynebor RM, et al. Among authors: chen mh. Bioorg Med Chem Lett. 2011 Jan 1;21(1):411-6. doi: 10.1016/j.bmcl.2010.10.128. Epub 2010 Oct 30. Bioorg Med Chem Lett. 2011. PMID: 21084192

5

Synthesis and biological activity of pyridopyridazin-6-one p38α MAP kinase inhibitors. Part 2.

Tynebor RM, Chen MH, Natarajan SR, O'Neill EA, Thompson JE, Fitzgerald CE, O'Keefe SJ, Doherty JB. Tynebor RM, et al. Among authors: chen mh. Bioorg Med Chem Lett. 2012 Sep 15;22(18):5979-83. doi: 10.1016/j.bmcl.2012.07.035. Epub 2012 Aug 2. Bioorg Med Chem Lett. 2012. PMID: 22901390

6

Synthesis and biological activities of spiroheterocyclic growth hormone secretagogues.

Chen MH, Pollard PP, Patchett AA, Cheng K, Wei L, Chan WW, Butler B, Jacks TM, Smith RG. Chen MH, et al. Bioorg Med Chem Lett. 1999 May 3;9(9):1261-6. doi: 10.1016/s0960-894x(99)00183-3. Bioorg Med Chem Lett. 1999. PMID: 10340611

7

Modeling directed design and biological evaluation of quinazolinones as non-peptidic growth hormone secretagogues.

Ye Z, Gao Y, Bakshi RK, Chen MH, Rohrer SP, Feighner SD, Pong SS, Howard AD, Blake A, Birzin ET, Locco L, Parmar RM, Chan WW, Schaeffer JM, Smith RG, Patchett AA, Nargund RP. Ye Z, et al. Among authors: chen mh. Bioorg Med Chem Lett. 2000 Jan 3;10(1):5-8. doi: 10.1016/s0960-894x(99)00584-3. Bioorg Med Chem Lett. 2000. PMID: 10636230

8

Carbohydroxamido-oxazolidines: antibacterial agents that target lipid A biosynthesis.

Chen MH, Steiner MG, de Laszlo SE, Patchett AA, Anderson MS, Hyland SA, Onishi HR, Silver LL, Raetz CR. Chen MH, et al. Bioorg Med Chem Lett. 1999 Feb 8;9(3):313-8. doi: 10.1016/s0960-894x(98)00749-5. Bioorg Med Chem Lett. 1999. PMID: 10091675

9

Discovery of T-1101 tosylate as a first-in-class clinical candidate for Hec1/Nek2 inhibition in cancer therapy.

Chuang SH, Lee YE, Huang LYL, Chen CK, Lai CL, Lin YH, Yang JY, Yang SC, Chang LH, Chen CH, Liu CW, Lin HS, Lee YR, Huang KP, Fu KC, Jen HM, Lai JY, Jian PS, Wang YC, Hsueh WY, Tsai PY, Hong WH, Chang CC, Wu DZ, Wu J, Chen MH, Yu KM, Chern CY, Chang JM, Lau JYN, Huang JJ. Chuang SH, et al. Among authors: chen ch, chen ck, chen mh. Eur J Med Chem. 2020 Apr 1;191:112118. doi: 10.1016/j.ejmech.2020.112118. Epub 2020 Feb 7. Eur J Med Chem. 2020. PMID: 32113126

10

Antibacterial agents that inhibit lipid A biosynthesis.

Onishi HR, Pelak BA, Gerckens LS, Silver LL, Kahan FM, Chen MH, Patchett AA, Galloway SM, Hyland SA, Anderson MS, Raetz CR. Onishi HR, et al. Among authors: chen mh. Science. 1996 Nov 8;274(5289):980-2. doi: 10.1126/science.274.5289.980. Science. 1996. PMID: 8875939

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