Chen L - Search Results

1

Cancer metabolism and tumor microenvironment: fostering each other?

Yuan Y, Li H, Pu W, Chen L, Guo D, Jiang H, He B, Qin S, Wang K, Li N, Feng J, Wen J, Cheng S, Zhang Y, Yang W, Ye D, Lu Z, Huang C, Mei J, Zhang HF, Gao P, Jiang P, Su S, Sun B, Zhao SM. Yuan Y, et al. Among authors: chen l. Sci China Life Sci. 2022 Feb;65(2):236-279. doi: 10.1007/s11427-021-1999-2. Epub 2021 Nov 26. Sci China Life Sci. 2022. PMID: 34846643 Review.

2

Insulin and mTOR Pathway Regulate HDAC3-Mediated Deacetylation and Activation of PGK1.

Wang S, Jiang B, Zhang T, Liu L, Wang Y, Wang Y, Chen X, Lin H, Zhou L, Xia Y, Chen L, Yang C, Xiong Y, Ye D, Guan KL. Wang S, et al. Among authors: chen l, chen x. PLoS Biol. 2015 Sep 10;13(9):e1002243. doi: 10.1371/journal.pbio.1002243. eCollection 2015. PLoS Biol. 2015. PMID: 26356530 Free PMC article.

3

Targeting IRG1 reverses the immunosuppressive function of tumor-associated macrophages and enhances cancer immunotherapy.

Chen YJ, Li GN, Li XJ, Wei LX, Fu MJ, Cheng ZL, Yang Z, Zhu GQ, Wang XD, Zhang C, Zhang JY, Sun YP, Saiyin H, Zhang J, Liu WR, Zhu WW, Guan KL, Xiong Y, Yang Y, Ye D, Chen LL. Chen YJ, et al. Sci Adv. 2023 Apr 28;9(17):eadg0654. doi: 10.1126/sciadv.adg0654. Epub 2023 Apr 28. Sci Adv. 2023. PMID: 37115931 Free PMC article.

4

Metabolic Reprogramming via ACOD1 depletion enhances function of human induced pluripotent stem cell-derived CAR-macrophages in solid tumors.

Wang X, Su S, Zhu Y, Cheng X, Cheng C, Chen L, Lei A, Zhang L, Xu Y, Ye D, Zhang Y, Li W, Zhang J. Wang X, et al. Among authors: chen l. Nat Commun. 2023 Sep 18;14(1):5778. doi: 10.1038/s41467-023-41470-9. Nat Commun. 2023. PMID: 37723178 Free PMC article.

5

Itaconate in host inflammation and defense.

Ye D, Wang P, Chen LL, Guan KL, Xiong Y. Ye D, et al. Trends Endocrinol Metab. 2024 Mar 5:S1043-2760(24)00033-X. doi: 10.1016/j.tem.2024.02.004. Online ahead of print. Trends Endocrinol Metab. 2024. PMID: 38448252 Review.

6

Regulation of G6PD acetylation by SIRT2 and KAT9 modulates NADPH homeostasis and cell survival during oxidative stress.

Wang YP, Zhou LS, Zhao YZ, Wang SW, Chen LL, Liu LX, Ling ZQ, Hu FJ, Sun YP, Zhang JY, Yang C, Yang Y, Xiong Y, Guan KL, Ye D. Wang YP, et al. EMBO J. 2014 Jun 17;33(12):1304-20. doi: 10.1002/embj.201387224. Epub 2014 Apr 25. EMBO J. 2014. PMID: 24769394 Free PMC article.

7

WT1 recruits TET2 to regulate its target gene expression and suppress leukemia cell proliferation.

Wang Y, Xiao M, Chen X, Chen L, Xu Y, Lv L, Wang P, Yang H, Ma S, Lin H, Jiao B, Ren R, Ye D, Guan KL, Xiong Y. Wang Y, et al. Among authors: chen l, chen x. Mol Cell. 2015 Feb 19;57(4):662-673. doi: 10.1016/j.molcel.2014.12.023. Epub 2015 Jan 15. Mol Cell. 2015. PMID: 25601757 Free PMC article.

8

SIRT5 inhibits peroxisomal ACOX1 to prevent oxidative damage and is downregulated in liver cancer.

Chen XF, Tian MX, Sun RQ, Zhang ML, Zhou LS, Jin L, Chen LL, Zhou WJ, Duan KL, Chen YJ, Gao C, Cheng ZL, Wang F, Zhang JY, Sun YP, Yu HX, Zhao YZ, Yang Y, Liu WR, Shi YH, Xiong Y, Guan KL, Ye D. Chen XF, et al. Among authors: chen ll, chen yj. EMBO Rep. 2018 May;19(5):e45124. doi: 10.15252/embr.201745124. Epub 2018 Feb 28. EMBO Rep. 2018. PMID: 29491006 Free PMC article.

9

SNIP1 Recruits TET2 to Regulate c-MYC Target Genes and Cellular DNA Damage Response.

Chen LL, Lin HP, Zhou WJ, He CX, Zhang ZY, Cheng ZL, Song JB, Liu P, Chen XY, Xia YK, Chen XF, Sun RQ, Zhang JY, Sun YP, Song L, Liu BJ, Du RK, Ding C, Lan F, Huang SL, Zhou F, Liu S, Xiong Y, Ye D, Guan KL. Chen LL, et al. Among authors: chen xy, chen xf. Cell Rep. 2018 Nov 6;25(6):1485-1500.e4. doi: 10.1016/j.celrep.2018.10.028. Cell Rep. 2018. PMID: 30404004 Free PMC article.

10

Itaconate inhibits TET DNA dioxygenases to dampen inflammatory responses.

Chen LL, Morcelle C, Cheng ZL, Chen X, Xu Y, Gao Y, Song J, Li Z, Smith MD, Shi M, Zhu Y, Zhou N, Cheng M, He C, Liu KY, Lu G, Zhang L, Zhang C, Zhang J, Sun Y, Qi T, Lyu Y, Ren ZZ, Tan XM, Yin J, Lan F, Liu Y, Yang H, Qian M, Duan C, Chang X, Zhou Y, Shen L, Baldwin AS, Guan KL, Xiong Y, Ye D. Chen LL, et al. Among authors: chen x. Nat Cell Biol. 2022 Mar;24(3):353-363. doi: 10.1038/s41556-022-00853-8. Epub 2022 Mar 7. Nat Cell Biol. 2022. PMID: 35256775 Free PMC article.

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