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High-throughput proteomic analysis of FFPE tissue samples facilitates tumor stratification.
Zhu Y, Weiss T, Zhang Q, Sun R, Wang B, Yi X, Wu Z, Gao H, Cai X, Ruan G, Zhu T, Xu C, Lou S, Yu X, Gillet L, Blattmann P, Saba K, Fankhauser CD, Schmid MB, Rutishauser D, Ljubicic J, Christiansen A, Fritz C, Rupp NJ, Poyet C, Rushing E, Weller M, Roth P, Haralambieva E, Hofer S, Chen C, Jochum W, Gao X, Teng X, Chen L, Zhong Q, Wild PJ, Aebersold R, Guo T. Zhu Y, et al. Among authors: chen l, chen c. Mol Oncol. 2019 Nov;13(11):2305-2328. doi: 10.1002/1878-0261.12570. Epub 2019 Sep 18. Mol Oncol. 2019. PMID: 31495056 Free PMC article.
Phenotype Classification using Proteome Data in a Data-Independent Acquisition Tensor Format.
Zhang F, Yu S, Wu L, Zang Z, Yi X, Zhu J, Lu C, Sun P, Sun Y, Selvarajan S, Chen L, Teng X, Zhao Y, Wang G, Xiao J, Huang S, Kon OL, Iyer NG, Li SZ, Luan Z, Guo T. Zhang F, et al. Among authors: chen l. J Am Soc Mass Spectrom. 2020 Nov 4;31(11):2296-2304. doi: 10.1021/jasms.0c00254. Epub 2020 Oct 26. J Am Soc Mass Spectrom. 2020. PMID: 33104352
Computational Optimization of Spectral Library Size Improves DIA-MS Proteome Coverage and Applications to 15 Tumors.
Ge W, Liang X, Zhang F, Hu Y, Xu L, Xiang N, Sun R, Liu W, Xue Z, Yi X, Sun Y, Wang B, Zhu J, Lu C, Zhan X, Chen L, Wu Y, Zheng Z, Gong W, Wu Q, Yu J, Ye Z, Teng X, Huang S, Zheng S, Liu T, Yuan C, Guo T. Ge W, et al. Among authors: chen l. J Proteome Res. 2021 Dec 3;20(12):5392-5401. doi: 10.1021/acs.jproteome.1c00640. Epub 2021 Nov 8. J Proteome Res. 2021. PMID: 34748352
Proteomics profiling of colorectal cancer progression identifies PLOD2 as a potential therapeutic target.
Shao Y, Xu K, Zheng X, Zhou B, Zhang X, Wang L, Sun Y, Li D, Chen T, Wang J, Yu S, Sun L, Xu X, Dai S, Gao H, Ruan G, Liu W, Cai X, Zhu T, Qi L, Chen J, Hu W, Weng X, Zhu Y, Xiang X, Hu Z, Li J, Chen L, Shao J, Zheng S, Guo T. Shao Y, et al. Among authors: chen j, chen l, chen t. Cancer Commun (Lond). 2022 Feb;42(2):164-169. doi: 10.1002/cac2.12240. Epub 2021 Dec 4. Cancer Commun (Lond). 2022. PMID: 34862750 Free PMC article. No abstract available.
Artificial intelligence defines protein-based classification of thyroid nodules.
Sun Y, Selvarajan S, Zang Z, Liu W, Zhu Y, Zhang H, Chen W, Chen H, Li L, Cai X, Gao H, Wu Z, Zhao Y, Chen L, Teng X, Mantoo S, Lim TK, Hariraman B, Yeow S, Alkaff SMF, Lee SS, Ruan G, Zhang Q, Zhu T, Hu Y, Dong Z, Ge W, Xiao Q, Wang W, Wang G, Xiao J, He Y, Wang Z, Sun W, Qin Y, Zhu J, Zheng X, Wang L, Zheng X, Xu K, Shao Y, Zheng S, Liu K, Aebersold R, Guan H, Wu X, Luo D, Tian W, Li SZ, Kon OL, Iyer NG, Guo T. Sun Y, et al. Among authors: chen l, chen w, chen h. Cell Discov. 2022 Sep 6;8(1):85. doi: 10.1038/s41421-022-00442-x. Cell Discov. 2022. PMID: 36068205 Free PMC article.
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