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Massively parallel base editing to map variant effects in human hematopoiesis.
Martin-Rufino JD, Castano N, Pang M, Grody EI, Joubran S, Caulier A, Wahlster L, Li T, Qiu X, Riera-Escandell AM, Newby GA, Al'Khafaji A, Chaudhary S, Black S, Weng C, Munson G, Liu DR, Wlodarski MW, Sims K, Oakley JH, Fasano RM, Xavier RJ, Lander ES, Klein DE, Sankaran VG. Martin-Rufino JD, et al. Among authors: chaudhary s. Cell. 2023 May 25;186(11):2456-2474.e24. doi: 10.1016/j.cell.2023.03.035. Epub 2023 May 2. Cell. 2023. PMID: 37137305 Free article.
A general approach to identify cell-permeable and synthetic anti-CRISPR small molecules.
Lim D, Zhou Q, Cox KJ, Law BK, Lee M, Kokkonda P, Sreekanth V, Pergu R, Chaudhary SK, Gangopadhyay SA, Maji B, Lai S, Amako Y, Thompson DB, Subramanian HKK, Mesleh MF, Dančík V, Clemons PA, Wagner BK, Woo CM, Church GM, Choudhary A. Lim D, et al. Among authors: chaudhary sk. Nat Cell Biol. 2022 Dec;24(12):1766-1775. doi: 10.1038/s41556-022-01005-8. Epub 2022 Nov 17. Nat Cell Biol. 2022. PMID: 36396978 Free PMC article.
Chemogenetic System Demonstrates That Cas9 Longevity Impacts Genome Editing Outcomes.
Sreekanth V, Zhou Q, Kokkonda P, Bermudez-Cabrera HC, Lim D, Law BK, Holmes BR, Chaudhary SK, Pergu R, Leger BS, Walker JA, Gifford DK, Sherwood RI, Choudhary A. Sreekanth V, et al. Among authors: chaudhary sk. ACS Cent Sci. 2020 Dec 23;6(12):2228-2237. doi: 10.1021/acscentsci.0c00129. Epub 2020 Nov 18. ACS Cent Sci. 2020. PMID: 33376784 Free PMC article.
Development and Applications of Chimera Platforms for Tyrosine Phosphorylation.
Pergu R, Shoba VM, Chaudhary SK, Munkanatta Godage DNP, Deb A, Singha S, Dhawa U, Singh P, Anokhina V, Singh S, Siriwardena SU, Choudhary A. Pergu R, et al. Among authors: chaudhary sk. ACS Cent Sci. 2023 Aug 9;9(8):1558-1566. doi: 10.1021/acscentsci.3c00200. eCollection 2023 Aug 23. ACS Cent Sci. 2023. PMID: 37637727 Free PMC article.
Phosphorylation-Inducing Chimeric Small Molecules.
Siriwardena SU, Munkanatta Godage DNP, Shoba VM, Lai S, Shi M, Wu P, Chaudhary SK, Schreiber SL, Choudhary A. Siriwardena SU, et al. Among authors: chaudhary sk. J Am Chem Soc. 2020 Aug 19;142(33):14052-14057. doi: 10.1021/jacs.0c05537. Epub 2020 Aug 4. J Am Chem Soc. 2020. PMID: 32787262
Unifying community-wide whole-brain imaging datasets enables robust automated neuron identification and reveals determinants of neuron positioning in C. elegans.
Sprague DY, Rusch K, Dunn RL, Borchardt JM, Bubnis G, Chiu GC, Wen C, Suzuki R, Chaudhary S, Dichter B, Ly R, Onami S, Lu H, Kimura K, Yemini EI, Kato S. Sprague DY, et al. Among authors: chaudhary s. bioRxiv [Preprint]. 2024 Apr 30:2024.04.28.591397. doi: 10.1101/2024.04.28.591397. bioRxiv. 2024. PMID: 38746302 Free PMC article. Preprint.
1,673 results