Chan BKC - Search Results

1

A Combinatorial CRISPR-Cas9 Screen Identifies Ifenprodil as an Adjunct to Sorafenib for Liver Cancer Treatment.

Xu F, Tong M, Tong CSW, Chan BKC, Chu HY, Wong TL, Fong JHC, Cheung MSH, Mak KH, Pardeshi L, Huang Y, Wong KH, Choi GCG, Ma S, Wong ASL. Xu F, et al. Among authors: chan bkc. Cancer Res. 2021 Dec 15;81(24):6219-6232. doi: 10.1158/0008-5472.CAN-21-1017. Epub 2021 Oct 19. Cancer Res. 2021. PMID: 34666996

2

A Three-Way Combinatorial CRISPR Screen for Analyzing Interactions among Druggable Targets.

Zhou P, Chan BKC, Wan YK, Yuen CTL, Choi GCG, Li X, Tong CSW, Zhong SSW, Sun J, Bao Y, Mak SYL, Chow MZY, Khaw JV, Leung SY, Zheng Z, Cheung LWT, Tan K, Wong KH, Chan HYE, Wong ASL. Zhou P, et al. Among authors: chan bkc. Cell Rep. 2020 Aug 11;32(6):108020. doi: 10.1016/j.celrep.2020.108020. Cell Rep. 2020. PMID: 32783942 Free article.

3

Extensible combinatorial CRISPR screening in mammalian cells.

Zhou P, Wan YK, Chan BKC, Choi GCG, Wong ASL. Zhou P, et al. Among authors: chan bkc. STAR Protoc. 2021 Jan 9;2(1):100255. doi: 10.1016/j.xpro.2020.100255. eCollection 2021 Mar 19. STAR Protoc. 2021. PMID: 33490975 Free PMC article.

4

Machine learning-coupled combinatorial mutagenesis enables resource-efficient engineering of CRISPR-Cas9 genome editor activities.

Thean DGL, Chu HY, Fong JHC, Chan BKC, Zhou P, Kwok CCS, Chan YM, Mak SYL, Choi GCG, Ho JWK, Zheng Z, Wong ASL. Thean DGL, et al. Among authors: chan bkc. Nat Commun. 2022 Apr 25;13(1):2219. doi: 10.1038/s41467-022-29874-5. Nat Commun. 2022. PMID: 35468907 Free PMC article.

5

Combinatorial mutagenesis en masse optimizes the genome editing activities of SpCas9.

Choi GCG, Zhou P, Yuen CTL, Chan BKC, Xu F, Bao S, Chu HY, Thean D, Tan K, Wong KH, Zheng Z, Wong ASL. Choi GCG, et al. Among authors: chan bkc. Nat Methods. 2019 Aug;16(8):722-730. doi: 10.1038/s41592-019-0473-0. Epub 2019 Jul 15. Nat Methods. 2019. PMID: 31308554

6

High-fidelity KKH variant of Staphylococcus aureus Cas9 nucleases with improved base mismatch discrimination.

Yuen CTL, Thean DGL, Chan BKC, Zhou P, Kwok CCS, Chu HY, Cheung MSH, Wang B, Chan YM, Mak SYL, Leung AY, Choi GCG, Zheng Z, Wong ASL. Yuen CTL, et al. Among authors: chan bkc. Nucleic Acids Res. 2022 Feb 22;50(3):1650-1660. doi: 10.1093/nar/gkab1291. Nucleic Acids Res. 2022. PMID: 35051997 Free PMC article.

7

Publisher Correction: Combinatorial mutagenesis en masse optimizes the genome editing activities of SpCas9.

Choi GCG, Zhou P, Yuen CTL, Chan BKC, Xu F, Bao S, Chu HY, Thean D, Tan K, Wong KH, Zheng Z, Wong ASL. Choi GCG, et al. Among authors: chan bkc. Nat Methods. 2019 Aug;16(8):789. doi: 10.1038/s41592-019-0533-5. Nat Methods. 2019. PMID: 31337886

8

Human Genetic Epidemiology Using R.

Chan BKC. Chan BKC. Adv Exp Med Biol. 2018;1082:217-341. doi: 10.1007/978-3-319-93791-5_5. Adv Exp Med Biol. 2018. PMID: 30357720

9

Applied Human Genetic Epidemiology.

Chan BKC. Chan BKC. Adv Exp Med Biol. 2018;1082:145-216. doi: 10.1007/978-3-319-93791-5_4. Adv Exp Med Biol. 2018. PMID: 30357719

10

Applied Statistics for Human Genetics Using R.

Chan BKC. Chan BKC. Adv Exp Med Biol. 2018;1082:123-144. doi: 10.1007/978-3-319-93791-5_3. Adv Exp Med Biol. 2018. PMID: 30357718

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