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Identification of Novel GSK-3β Hits Using Competitive Biophysical Assays.
Balboni B, Tripathi SK, Veronesi M, Russo D, Penna I, Giabbai B, Bandiera T, Storici P, Girotto S, Cavalli A. Balboni B, et al. Among authors: cavalli a. Int J Mol Sci. 2022 Mar 31;23(7):3856. doi: 10.3390/ijms23073856. Int J Mol Sci. 2022. PMID: 35409221 Free PMC article.
A binding site for nonsteroidal anti-inflammatory drugs in fatty acid amide hydrolase.
Bertolacci L, Romeo E, Veronesi M, Magotti P, Albani C, Dionisi M, Lambruschini C, Scarpelli R, Cavalli A, De Vivo M, Piomelli D, Garau G. Bertolacci L, et al. Among authors: cavalli a. J Am Chem Soc. 2013 Jan 9;135(1):22-5. doi: 10.1021/ja308733u. Epub 2012 Dec 21. J Am Chem Soc. 2013. PMID: 23240907 Free PMC article.
Synthesis and structure-activity relationship (SAR) of 2-methyl-4-oxo-3-oxetanylcarbamic acid esters, a class of potent N-acylethanolamine acid amidase (NAAA) inhibitors.
Ponzano S, Bertozzi F, Mengatto L, Dionisi M, Armirotti A, Romeo E, Berteotti A, Fiorelli C, Tarozzo G, Reggiani A, Duranti A, Tarzia G, Mor M, Cavalli A, Piomelli D, Bandiera T. Ponzano S, et al. Among authors: cavalli a. J Med Chem. 2013 Sep 12;56(17):6917-34. doi: 10.1021/jm400739u. Epub 2013 Aug 30. J Med Chem. 2013. PMID: 23991897 Free article.
Synthesis, structure-activity, and structure-stability relationships of 2-substituted-N-(4-oxo-3-oxetanyl) N-acylethanolamine acid amidase (NAAA) inhibitors.
Vitale R, Ottonello G, Petracca R, Bertozzi SM, Ponzano S, Armirotti A, Berteotti A, Dionisi M, Cavalli A, Piomelli D, Bandiera T, Bertozzi F. Vitale R, et al. Among authors: cavalli a. ChemMedChem. 2014 Feb;9(2):323-36. doi: 10.1002/cmdc.201300416. Epub 2014 Jan 8. ChemMedChem. 2014. PMID: 24403170 Free article.
Multitarget drug discovery for Alzheimer's disease: triazinones as BACE-1 and GSK-3β inhibitors.
Prati F, De Simone A, Bisignano P, Armirotti A, Summa M, Pizzirani D, Scarpelli R, Perez DI, Andrisano V, Perez-Castillo A, Monti B, Massenzio F, Polito L, Racchi M, Favia AD, Bottegoni G, Martinez A, Bolognesi ML, Cavalli A. Prati F, et al. Among authors: cavalli a. Angew Chem Int Ed Engl. 2015 Jan 26;54(5):1578-82. doi: 10.1002/anie.201410456. Epub 2014 Dec 11. Angew Chem Int Ed Engl. 2015. PMID: 25504761 Free article.
3,4-Dihydro-1,3,5-triazin-2(1H)-ones as the First Dual BACE-1/GSK-3β Fragment Hits against Alzheimer's Disease.
Prati F, De Simone A, Armirotti A, Summa M, Pizzirani D, Scarpelli R, Bertozzi SM, Perez DI, Andrisano V, Perez-Castillo A, Monti B, Massenzio F, Polito L, Racchi M, Sabatino P, Bottegoni G, Martinez A, Cavalli A, Bolognesi ML. Prati F, et al. Among authors: cavalli a. ACS Chem Neurosci. 2015 Oct 21;6(10):1665-82. doi: 10.1021/acschemneuro.5b00121. Epub 2015 Aug 3. ACS Chem Neurosci. 2015. PMID: 26171616 Free article.
695 results