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Combinatorial targeting of G-protein-coupled bile acid receptor 1 and cysteinyl leukotriene receptor 1 reveals a mechanistic role for bile acids and leukotrienes in drug-induced liver injury.
Biagioli M, Marchianò S, di Giorgio C, Roselli R, Bordoni M, Bellini R, Fiorillo B, Sepe V, Catalanotti B, Cassiano C, Monti MC, Distrutti E, Zampella A, Fiorucci S. Biagioli M, et al. Among authors: cassiano c. Hepatology. 2023 Jul 1;78(1):26-44. doi: 10.1002/hep.32787. Epub 2022 Oct 12. Hepatology. 2023. PMID: 36107019
Chemical proteomics-driven discovery of oleocanthal as an Hsp90 inhibitor.
Margarucci L, Monti MC, Cassiano C, Mozzicafreddo M, Angeletti M, Riccio R, Tosco A, Casapullo A. Margarucci L, et al. Among authors: cassiano c. Chem Commun (Camb). 2013 Jul 4;49(52):5844-6. doi: 10.1039/c3cc41858h. Epub 2013 May 24. Chem Commun (Camb). 2013. PMID: 23703283
Novel Isoxazole Derivatives with Potent FXR Agonistic Activity Prevent Acetaminophen-Induced Liver Injury.
Sepe V, Marchianò S, Finamore C, Baronissi G, Di Leva FS, Carino A, Biagioli M, Fiorucci C, Cassiano C, Monti MC, Del Gaudio F, Novellino E, Limongelli V, Fiorucci S, Zampella A. Sepe V, et al. Among authors: cassiano c. ACS Med Chem Lett. 2018 Dec 6;10(4):407-412. doi: 10.1021/acsmedchemlett.8b00423. eCollection 2019 Apr 11. ACS Med Chem Lett. 2018. PMID: 30996771 Free PMC article.
35 results