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Discovery of New Broad-Spectrum Anti-Infectives for Eukaryotic Pathogens Using Bioorganometallic Chemistry.
Lin Y, Jung H, Bulman CA, Ng J, Vinck R, O'Beirne C, Zhong S, Moser MS, Tricoche N, Peguero R, Li RW, Urban JF Jr, Le Pape P, Pagniez F, Moretto M, Weil T, Lustigman S, Cariou K, Mitreva M, Sakanari JA, Gasser G. Lin Y, et al. Among authors: cariou k. J Med Chem. 2023 Dec 14;66(23):15867-15882. doi: 10.1021/acs.jmedchem.3c01333. Epub 2023 Nov 27. J Med Chem. 2023. PMID: 38009931
In vivo active organometallic-containing antimycotic agents.
Rubbiani R, Weil T, Tocci N, Mastrobuoni L, Jeger S, Moretto M, Ng J, Lin Y, Hess J, Ferrari S, Kaech A, Young L, Spencer J, Moore AL, Cariou K, Renga G, Pariano M, Romani L, Gasser G. Rubbiani R, et al. Among authors: cariou k. RSC Chem Biol. 2021 Jul 8;2(4):1263-1273. doi: 10.1039/d1cb00123j. eCollection 2021 Aug 5. RSC Chem Biol. 2021. PMID: 34458840 Free PMC article.
Metallodrug Profiling against SARS-CoV-2 Target Proteins Identifies Highly Potent Inhibitors of the S/ACE2 interaction and the Papain-like Protease PLpro.
Gil-Moles M, Türck S, Basu U, Pettenuzzo A, Bhattacharya S, Rajan A, Ma X, Büssing R, Wölker J, Burmeister H, Hoffmeister H, Schneeberg P, Prause A, Lippmann P, Kusi-Nimarko J, Hassell-Hart S, McGown A, Guest D, Lin Y, Notaro A, Vinck R, Karges J, Cariou K, Peng K, Qin X, Wang X, Skiba J, Szczupak Ł, Kowalski K, Schatzschneider U, Hemmert C, Gornitzka H, Milaeva ER, Nazarov AA, Gasser G, Spencer J, Ronconi L, Kortz U, Cinatl J, Bojkova D, Ott I. Gil-Moles M, et al. Among authors: cariou k. Chemistry. 2021 Dec 20;27(71):17928-17940. doi: 10.1002/chem.202103258. Epub 2021 Nov 23. Chemistry. 2021. PMID: 34714566 Free PMC article.
46 results