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Design, Synthesis and Characterization of a Visible-Light-Sensitive Molecular Switch and Its PEGylation Towards a Self-Assembling Molecule.
Paolino M, Saletti M, Reale A, Licciardi M, Varvarà P, Marquette A, Léonard J, Bonechi C, Donati A, Giorgi G, Giuliani G, Carlotti B, Ortica F, Latterini L, Gentile M, Paccagnini E, Olivucci M, Cappelli A. Paolino M, et al. Among authors: cappelli a. Chemistry. 2022 Sep 6;28(50):e202201477. doi: 10.1002/chem.202201477. Epub 2022 Jul 13. Chemistry. 2022. PMID: 35695822 Free PMC article.
Novel potent and selective central 5-HT3 receptor ligands provided with different intrinsic efficacy. 2. Molecular basis of the intrinsic efficacy of arylpiperazine derivatives at the central 5-HT3 receptors.
Cappelli A, Anzini M, Vomero S, Canullo L, Mennuni L, Makovec F, Doucet E, Hamon M, Menziani MC, De Benedetti PG, Bruni G, Romeo MR, Giorgi G, Donati A. Cappelli A, et al. J Med Chem. 1999 May 6;42(9):1556-75. doi: 10.1021/jm981112s. J Med Chem. 1999. PMID: 10229626
A non-peptide NK1 receptor agonist showing subpicomolar affinity.
Cappelli A, Giuliani G, Pericot Mohr Gl Gl, Gallelli A, Anzini M, Vomero S, Cupello A, Scarrone S, Matarrese M, Moresco RM, Fazio F, Finetti F, Morbidelli L, Ziche M. Cappelli A, et al. J Med Chem. 2004 Mar 11;47(6):1315-8. doi: 10.1021/jm034219a. J Med Chem. 2004. PMID: 14998319
Further studies on imidazo[4,5-b]pyridine AT1 angiotensin II receptor antagonists. Effects of the transformation of the 4-phenylquinoline backbone into 4-phenylisoquinolinone or 1-phenylindene scaffolds.
Cappelli A, Pericot Mohr Gl, Giuliani G, Galeazzi S, Anzini M, Mennuni L, Ferrari F, Makovec F, Kleinrath EM, Langer T, Valoti M, Giorgi G, Vomero S. Cappelli A, et al. J Med Chem. 2006 Nov 2;49(22):6451-64. doi: 10.1021/jm0603163. J Med Chem. 2006. PMID: 17064065
362 results