Camphausen RT - Search Results

1

Quinic acid derivatives as sialyl Lewis(x)-mimicking selectin inhibitors: design, synthesis, and crystal structure in complex with E-selectin.

Kaila N, Somers WS, Thomas BE, Thakker P, Janz K, DeBernardo S, Tam S, Moore WJ, Yang R, Wrona W, Bedard PW, Crommie D, Keith JC Jr, Tsao DH, Alvarez JC, Ni H, Marchese E, Patton JT, Magnani JL, Camphausen RT. Kaila N, et al. Among authors: camphausen rt. J Med Chem. 2005 Jun 30;48(13):4346-57. doi: 10.1021/jm050049l. J Med Chem. 2005. PMID: 15974587

2

Beta-C-mannosides as selectin inhibitors.

Kaila N, Chen L, Thomas BE 4th, Tsao D, Tam S, Bedard PW, Camphausen RT, Alvarez JC, Ullas G. Kaila N, et al. Among authors: camphausen rt. J Med Chem. 2002 Apr 11;45(8):1563-6. doi: 10.1021/jm010390f. J Med Chem. 2002. PMID: 11931610

3

Synthesis and biological evaluation of quinoline salicylic acids as P-selectin antagonists.

Kaila N, Janz K, DeBernardo S, Bedard PW, Camphausen RT, Tam S, Tsao DH, Keith JC Jr, Nickerson-Nutter C, Shilling A, Young-Sciame R, Wang Q. Kaila N, et al. Among authors: camphausen rt. J Med Chem. 2007 Jan 11;50(1):21-39. doi: 10.1021/jm0602256. J Med Chem. 2007. PMID: 17201408

4

2-(4-Chlorobenzyl)-3-hydroxy-7,8,9,10-tetrahydrobenzo[H]quinoline-4-carboxylic acid (PSI-697): identification of a clinical candidate from the quinoline salicylic acid series of P-selectin antagonists.

Kaila N, Janz K, Huang A, Moretto A, DeBernardo S, Bedard PW, Tam S, Clerin V, Keith JC Jr, Tsao DH, Sushkova N, Shaw GD, Camphausen RT, Schaub RG, Wang Q. Kaila N, et al. Among authors: camphausen rt. J Med Chem. 2007 Jan 11;50(1):40-64. doi: 10.1021/jm060631p. J Med Chem. 2007. PMID: 17201409

5

Design and synthesis of sialyl Lewis x mimics as E-selectin inhibitors.

Kaila N, Thomas BE 4th, Thakker P, Alvarez JC, Camphausen RT, Crommie D. Kaila N, et al. Among authors: camphausen rt. Bioorg Med Chem Lett. 2001 Jan 22;11(2):151-5. doi: 10.1016/s0960-894x(00)00623-5. Bioorg Med Chem Lett. 2001. PMID: 11206447

6

Identification and structural determination of a potent P-selectin inhibitor.

Kaila N, Xu GY, Camphausen RT, Xiang Y. Kaila N, et al. Among authors: camphausen rt. Bioorg Med Chem. 2001 Mar;9(3):801-6. doi: 10.1016/s0968-0896(00)00298-4. Bioorg Med Chem. 2001. PMID: 11310615

7

Insights into the molecular basis of leukocyte tethering and rolling revealed by structures of P- and E-selectin bound to SLe(X) and PSGL-1.

Somers WS, Tang J, Shaw GD, Camphausen RT. Somers WS, et al. Among authors: camphausen rt. Cell. 2000 Oct 27;103(3):467-79. doi: 10.1016/s0092-8674(00)00138-0. Cell. 2000. PMID: 11081633 Free article.

8

Sialyl Lewis(x)-mediated, PSGL-1-independent rolling adhesion on P-selectin.

Rodgers SD, Camphausen RT, Hammer DA. Rodgers SD, et al. Among authors: camphausen rt. Biophys J. 2000 Aug;79(2):694-706. doi: 10.1016/S0006-3495(00)76328-4. Biophys J. 2000. PMID: 10920004 Free PMC article.

9

A sulfated peptide segment at the amino terminus of PSGL-1 is critical for P-selectin binding.

Sako D, Comess KM, Barone KM, Camphausen RT, Cumming DA, Shaw GD. Sako D, et al. Among authors: camphausen rt. Cell. 1995 Oct 20;83(2):323-31. doi: 10.1016/0092-8674(95)90173-6. Cell. 1995. PMID: 7585949 Free article.

10

Isolated P-selectin glycoprotein ligand-1 dynamic adhesion to P- and E-selectin.

Goetz DJ, Greif DM, Ding H, Camphausen RT, Howes S, Comess KM, Snapp KR, Kansas GS, Luscinskas FW. Goetz DJ, et al. Among authors: camphausen rt. J Cell Biol. 1997 Apr 21;137(2):509-19. doi: 10.1083/jcb.137.2.509. J Cell Biol. 1997. PMID: 9128259 Free PMC article.

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