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C7a, a biphosphinic cyclopalladated compound, efficiently controls the development of a patient-derived xenograft model of adult T cell leukemia/lymphoma.
Guimaraes-Correa AB, Crawford LB, Figueiredo CR, Gimenes KP, Pinto LA, Grassi MFR, Feuer G, Travassos LR, Caires ACF, Rodrigues EG, Marriott SJ. Guimaraes-Correa AB, et al. Among authors: caires acf. Viruses. 2011 Jul;3(7):1041-1058. doi: 10.3390/v3071041. Epub 2011 Jul 5. Viruses. 2011. PMID: 21994769 Free PMC article.
A cyclopalladated complex interacts with mitochondrial membrane thiol-groups and induces the apoptotic intrinsic pathway in murine and cisplatin-resistant human tumor cells.
Serrano FA, Matsuo AL, Monteforte PT, Bechara A, Smaili SS, Santana DP, Rodrigues T, Pereira FV, Silva LS, Machado J Jr, Santos EL, Pesquero JB, Martins RM, Travassos LR, Caires AC, Rodrigues EG. Serrano FA, et al. BMC Cancer. 2011 Jul 14;11:296. doi: 10.1186/1471-2407-11-296. BMC Cancer. 2011. PMID: 21756336 Free PMC article.
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