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CAR+ and CAR- T cells share a differentiation trajectory into an NK-like subset after CD19 CAR T cell infusion in patients with B cell malignancies.
Louie RHY, Cai C, Samir J, Singh M, Deveson IW, Ferguson JM, Amos TG, McGuire HM, Gowrishankar K, Adikari T, Balderas R, Bonomi M, Ruella M, Bishop D, Gottlieb D, Blyth E, Micklethwaite K, Luciani F. Louie RHY, et al. Among authors: cai c. Nat Commun. 2023 Nov 27;14(1):7767. doi: 10.1038/s41467-023-43656-7. Nat Commun. 2023. PMID: 38012187 Free PMC article.
B-cell receptor reconstruction from single-cell RNA-seq with VDJPuzzle.
Rizzetto S, Koppstein DNP, Samir J, Singh M, Reed JH, Cai CH, Lloyd AR, Eltahla AA, Goodnow CC, Luciani F. Rizzetto S, et al. Among authors: cai ch. Bioinformatics. 2018 Aug 15;34(16):2846-2847. doi: 10.1093/bioinformatics/bty203. Bioinformatics. 2018. PMID: 29659703
Single-Cell Transcriptome Analysis of T Cells.
Van Der Byl W, Rizzetto S, Samir J, Cai C, Eltahla AA, Luciani F. Van Der Byl W, et al. Among authors: cai c. Methods Mol Biol. 2019;2048:155-205. doi: 10.1007/978-1-4939-9728-2_16. Methods Mol Biol. 2019. PMID: 31396939
Investigation of product-derived lymphoma following infusion of piggyBac-modified CD19 chimeric antigen receptor T cells.
Micklethwaite KP, Gowrishankar K, Gloss BS, Li Z, Street JA, Moezzi L, Mach MA, Sutrave G, Clancy LE, Bishop DC, Louie RHY, Cai C, Foox J, MacKay M, Sedlazeck FJ, Blombery P, Mason CE, Luciani F, Gottlieb DJ, Blyth E. Micklethwaite KP, et al. Among authors: cai c. Blood. 2021 Oct 21;138(16):1391-1405. doi: 10.1182/blood.2021010858. Blood. 2021. PMID: 33974080 Free PMC article. Clinical Trial.
Identification of human progenitors of exhausted CD8+ T cells associated with elevated IFN-γ response in early phase of viral infection.
Cai C, Samir J, Pirozyan MR, Adikari TN, Gupta M, Leung P, Hughes B, Van der Byl W, Rizzetto S, Elthala A, Keoshkerian E, Palgen JL, Peters T, Nguyen THO, Louie R, Kedzierska K, Gaudieri S, Bull RA, Lloyd AR, Luciani F. Cai C, et al. Nat Commun. 2022 Dec 7;13(1):7543. doi: 10.1038/s41467-022-35281-7. Nat Commun. 2022. PMID: 36477661 Free PMC article.
Ancestral SARS-CoV-2-specific T cells cross-recognize the Omicron variant.
Gao Y, Cai C, Grifoni A, Müller TR, Niessl J, Olofsson A, Humbert M, Hansson L, Österborg A, Bergman P, Chen P, Olsson A, Sandberg JK, Weiskopf D, Price DA, Ljunggren HG, Karlsson AC, Sette A, Aleman S, Buggert M. Gao Y, et al. Among authors: cai c. Nat Med. 2022 Mar;28(3):472-476. doi: 10.1038/s41591-022-01700-x. Epub 2022 Jan 14. Nat Med. 2022. PMID: 35042228 Free PMC article.
SARS-CoV-2 vaccination enhances the effector qualities of spike-specific T cells induced by COVID-19.
Cai C, Gao Y, Adamo S, Rivera-Ballesteros O, Hansson L, Österborg A, Bergman P, Sandberg JK, Ljunggren HG, Björkström NK, Strålin K, Llewellyn-Lacey S, Price DA, Qin C, Grifoni A, Weiskopf D, Wherry EJ, Sette A, Aleman S, Buggert M. Cai C, et al. Sci Immunol. 2023 Dec 8;8(90):eadh0687. doi: 10.1126/sciimmunol.adh0687. Epub 2023 Dec 8. Sci Immunol. 2023. PMID: 38064569 Free PMC article.
5,056 results