Extraneural metastatic ependymoma: distant metastasis to the pleura, lungs, lymph nodes and bone

BMJ Case Rep. 2024 May 10;17(5):e259803. doi: 10.1136/bcr-2024-259803.

Abstract

Ependymomas are neuroepithelial tumours arising from ependymal cells surrounding the cerebral ventricles that rarely metastasise to extraneural structures. This spread has been reported to occur to the lungs, lymph nodes, liver and bone. We describe the case of a patient with recurrent CNS WHO grade 3 ependymoma with extraneural metastatic disease. He was treated with multiple surgical resections, radiation therapy and salvage chemotherapy for his extraneural metastasis to the lungs, bone, pleural space and lymph nodes.

Keywords: Cancer intervention; Neurooncology.

Publication types

  • Case Reports

MeSH terms

  • Bone Neoplasms* / secondary
  • Brain Neoplasms / diagnostic imaging
  • Brain Neoplasms / secondary
  • Ependymoma* / diagnostic imaging
  • Ependymoma* / pathology
  • Ependymoma* / secondary
  • Humans
  • Lung Neoplasms* / pathology
  • Lung Neoplasms* / secondary
  • Lymph Nodes / diagnostic imaging
  • Lymph Nodes / pathology
  • Lymphatic Metastasis / diagnostic imaging
  • Male
  • Pleural Neoplasms* / diagnostic imaging
  • Pleural Neoplasms* / pathology
  • Pleural Neoplasms* / secondary