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Chemotherapy-induced transposable elements activate MDA5 to enhance haematopoietic regeneration.
Clapes T, Polyzou A, Prater P, Sagar, Morales-Hernández A, Ferrarini MG, Kehrer N, Lefkopoulos S, Bergo V, Hummel B, Obier N, Maticzka D, Bridgeman A, Herman JS, Ilik I, Klaeylé L, Rehwinkel J, McKinney-Freeman S, Backofen R, Akhtar A, Cabezas-Wallscheid N, Sawarkar R, Rebollo R, Grün D, Trompouki E. Clapes T, et al. Nat Cell Biol. 2021 Jul;23(7):704-717. doi: 10.1038/s41556-021-00707-9. Epub 2021 Jul 12. Nat Cell Biol. 2021. PMID: 34253898 Free PMC article.
Haematopoietic stem cells in perisinusoidal niches are protected from ageing.
Saçma M, Pospiech J, Bogeska R, de Back W, Mallm JP, Sakk V, Soller K, Marka G, Vollmer A, Karns R, Cabezas-Wallscheid N, Trumpp A, Méndez-Ferrer S, Milsom MD, Mulaw MA, Geiger H, Florian MC. Saçma M, et al. Nat Cell Biol. 2019 Nov;21(11):1309-1320. doi: 10.1038/s41556-019-0418-y. Epub 2019 Nov 4. Nat Cell Biol. 2019. PMID: 31685996
Niche derived netrin-1 regulates hematopoietic stem cell dormancy via its receptor neogenin-1.
Renders S, Svendsen AF, Panten J, Rama N, Maryanovich M, Sommerkamp P, Ladel L, Redavid AR, Gibert B, Lazare S, Ducarouge B, Schönberger K, Narr A, Tourbez M, Dethmers-Ausema B, Zwart E, Hotz-Wagenblatt A, Zhang D, Korn C, Zeisberger P, Przybylla A, Sohn M, Mendez-Ferrer S, Heikenwälder M, Brune M, Klimmeck D, Bystrykh L, Frenette PS, Mehlen P, de Haan G, Cabezas-Wallscheid N, Trumpp A. Renders S, et al. Nat Commun. 2021 Jan 27;12(1):608. doi: 10.1038/s41467-020-20801-0. Nat Commun. 2021. PMID: 33504783 Free PMC article.
Publisher Correction: Chemotherapy-induced transposable elements activate MDA5 to enhance haematopoietic regeneration.
Clapes T, Polyzou A, Prater P, Sagar, Morales-Hernández A, Ferrarini MG, Kehrer N, Lefkopoulos S, Bergo V, Hummel B, Obier N, Maticzka D, Bridgeman A, Herman JS, Ilik I, Klaeylé L, Rehwinkel J, McKinney-Freeman S, Backofen R, Akhtar A, Cabezas-Wallscheid N, Sawarkar R, Rebollo R, Grün D, Trompouki E. Clapes T, et al. Nat Cell Biol. 2021 Dec;23(12):1338. doi: 10.1038/s41556-021-00785-9. Nat Cell Biol. 2021. PMID: 34611323 Free PMC article. No abstract available.
Multilayer omics analysis reveals a non-classical retinoic acid signaling axis that regulates hematopoietic stem cell identity.
Schönberger K, Obier N, Romero-Mulero MC, Cauchy P, Mess J, Pavlovich PV, Zhang YW, Mitterer M, Rettkowski J, Lalioti ME, Jäcklein K, Curtis JD, Féret B, Sommerkamp P, Morganti C, Ito K, Ghyselinck NB, Trompouki E, Buescher JM, Pearce EL, Cabezas-Wallscheid N. Schönberger K, et al. Cell Stem Cell. 2022 Jan 6;29(1):131-148.e10. doi: 10.1016/j.stem.2021.10.002. Epub 2021 Oct 26. Cell Stem Cell. 2022. PMID: 34706256 Free PMC article.
Hyaluronic acid-GPRC5C signalling promotes dormancy in haematopoietic stem cells.
Zhang YW, Mess J, Aizarani N, Mishra P, Johnson C, Romero-Mulero MC, Rettkowski J, Schönberger K, Obier N, Jäcklein K, Woessner NM, Lalioti ME, Velasco-Hernandez T, Sikora K, Wäsch R, Lehnertz B, Sauvageau G, Manke T, Menendez P, Walter SG, Minguet S, Laurenti E, Günther S, Grün D, Cabezas-Wallscheid N. Zhang YW, et al. Nat Cell Biol. 2022 Jul;24(7):1038-1048. doi: 10.1038/s41556-022-00931-x. Epub 2022 Jun 20. Nat Cell Biol. 2022. PMID: 35725769 Free PMC article.
TFEB induces mitochondrial itaconate synthesis to suppress bacterial growth in macrophages.
Schuster EM, Epple MW, Glaser KM, Mihlan M, Lucht K, Zimmermann JA, Bremser A, Polyzou A, Obier N, Cabezas-Wallscheid N, Trompouki E, Ballabio A, Vogel J, Buescher JM, Westermann AJ, Rambold AS. Schuster EM, et al. Nat Metab. 2022 Jul;4(7):856-866. doi: 10.1038/s42255-022-00605-w. Epub 2022 Jul 21. Nat Metab. 2022. PMID: 35864246 Free PMC article.
53 results