Brynda J - Search Results

1

Molecular Mechanism of LEDGF/p75 Dimerization.

Lux V, Brouns T, Čermáková K, Srb P, Fábry M, Mádlíková M, Hořejší M, Kukačka Z, Novák P, Kugler M, Brynda J, DeRijck J, Christ F, Debyser Z, Veverka V. Lux V, et al. Among authors: brynda j. Structure. 2020 Dec 1;28(12):1288-1299.e7. doi: 10.1016/j.str.2020.08.012. Epub 2020 Sep 17. Structure. 2020. PMID: 32946742 Free article.

2

The Gag-Pol encoded proteinase of an avian retrovirus expressed in E. coli can produce a novel proteinase (PR + IleGly) that is two amino acids larger at its carboxy-terminal region than the major Gag proteinase (PR).

Brynda J, Fábry M, Horejsí M, Sedlácek J. Brynda J, et al. Virology. 1995 Feb 20;207(1):185-90. doi: 10.1006/viro.1995.1065. Virology. 1995. PMID: 7871726 Free article.

3

A rapid screening method for biological activity of human immunodeficiency virus proteinase inhibitors by using a recombinant DNA-derived bacterial system.

Sedlácek J, Fábry M, Horejsí M, Brynda J, Luftig RB, Majer P. Sedlácek J, et al. Among authors: brynda j. Anal Biochem. 1993 Dec;215(2):306-9. doi: 10.1006/abio.1993.1593. Anal Biochem. 1993. PMID: 8122796 No abstract available.

4

Processing, purification, and kinetic characterization of the Gag-Pol encoded retroviral proteinase of myeloblastosis associated virus expressed in E. coli.

Brynda J, Fábry M, Tichý PJ, Horejsí M, Sedlácek J. Brynda J, et al. Adv Exp Med Biol. 1995;362:485-8. doi: 10.1007/978-1-4615-1871-6_64. Adv Exp Med Biol. 1995. PMID: 8540362 No abstract available.

5

Anti-HIV proteinase monoclonal antibody F11.2.32 that inhibits enzyme activity.

Stouracova R, Lescar J, Brynda J, Riottot MM, Chitarra V, Fabry M, Horejsi M, Rezacova P, Bentley G, Sedlacek J. Stouracova R, et al. Among authors: brynda j. Gen Physiol Biophys. 1998 Jun;17 Suppl 1:6-8. Gen Physiol Biophys. 1998. PMID: 9789741 No abstract available.

6

Structural basis of HIV-1 and HIV-2 protease inhibition by a monoclonal antibody.

Rezacova P, Lescar J, Brynda J, Fabry M, Horejsi M, Sedlacek J, Bentley GA. Rezacova P, et al. Among authors: brynda j. Structure. 2001 Oct;9(10):887-95. doi: 10.1016/s0969-2126(01)00654-2. Structure. 2001. PMID: 11591344 Free article.

7

Inhibition of HIV protease by monoclonal antibodies.

Rezacova P, Brynda J, Fabry M, Horejsi M, Stouracova R, Lescar J, Chitarra V, Riottot MM, Sedlacek J, Bentley GA. Rezacova P, et al. Among authors: brynda j. J Mol Recognit. 2002 Sep-Oct;15(5):272-6. doi: 10.1002/jmr.587. J Mol Recognit. 2002. PMID: 12447903 Review.

8

A phenylnorstatine inhibitor binding to HIV-1 protease: geometry, protonation, and subsite-pocket interactions analyzed at atomic resolution.

Brynda J, Rezacova P, Fabry M, Horejsi M, Stouracova R, Sedlacek J, Soucek M, Hradilek M, Lepsik M, Konvalinka J. Brynda J, et al. J Med Chem. 2004 Apr 8;47(8):2030-6. doi: 10.1021/jm031105q. J Med Chem. 2004. PMID: 15056001

9

Inhibitor binding at the protein interface in crystals of a HIV-1 protease complex.

Brynda J, Rezácová P, Fábry M, Horejsí M, Stouracová R, Soucek M, Hradílek M, Konvalinka J, Sedlácek J. Brynda J, et al. Acta Crystallogr D Biol Crystallogr. 2004 Nov;60(Pt 11):1943-8. doi: 10.1107/S0907444904021572. Epub 2004 Oct 20. Acta Crystallogr D Biol Crystallogr. 2004. PMID: 15502300

10

Role of hydroxyl group and R/S configuration of isostere in binding properties of HIV-1 protease inhibitors.

Petroková H, Dusková J, Dohnálek J, Skálová T, Vondrácková-Buchtelová E, Soucek M, Konvalinka J, Brynda J, Fábry M, Sedlácek J, Hasek J. Petroková H, et al. Among authors: brynda j. Eur J Biochem. 2004 Nov;271(22):4451-61. doi: 10.1111/j.1432-1033.2004.04384.x. Eur J Biochem. 2004. PMID: 15560786 Free article.

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