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Carborane-based carbonic anhydrase inhibitors.
Brynda J, Mader P, Šícha V, Fábry M, Poncová K, Bakardiev M, Grüner B, Cígler P, Řezáčová P. Brynda J, et al. Angew Chem Int Ed Engl. 2013 Dec 16;52(51):13760-3. doi: 10.1002/anie.201307583. Epub 2013 Nov 4. Angew Chem Int Ed Engl. 2013. PMID: 24307504
A distinct binding mode of a hydroxyethylamine isostere inhibitor of HIV-1 protease.
Dohnálek J, Hasek J, Dusková J, Petroková H, Hradilek M, Soucek M, Konvalinka J, Brynda J, Sedlácek J, Fábry M. Dohnálek J, et al. Among authors: brynda j. Acta Crystallogr D Biol Crystallogr. 2001 Mar;57(Pt 3):472-6. doi: 10.1107/s0907444900018928. Acta Crystallogr D Biol Crystallogr. 2001. PMID: 11223536
Hydroxyethylamine isostere of an HIV-1 protease inhibitor prefers its amine to the hydroxy group in binding to catalytic aspartates. A synchrotron study of HIV-1 protease in complex with a peptidomimetic inhibitor.
Dohnálek J, Hasek J, Dusková J, Petroková H, Hradilek M, Soucek M, Konvalinka J, Brynda J, Sedlácek J, Fábry M. Dohnálek J, et al. Among authors: brynda j. J Med Chem. 2002 Mar 28;45(7):1432-8. doi: 10.1021/jm010979e. J Med Chem. 2002. PMID: 11906284
120 results