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Differential Effects of p38, MAPK, PI3K or Rho Kinase Inhibitors on Bacterial Phagocytosis and Efferocytosis by Macrophages in COPD.
Bewley MA, Belchamber KB, Chana KK, Budd RC, Donaldson G, Wedzicha JA, Brightling CE, Kilty I, Donnelly LE, Barnes PJ, Singh D, Whyte MK, Dockrell DH; COPDMAP. Bewley MA, et al. Among authors: brightling ce. PLoS One. 2016 Sep 28;11(9):e0163139. doi: 10.1371/journal.pone.0163139. eCollection 2016. PLoS One. 2016. PMID: 27680884 Free PMC article.
Eosinophilic inflammation in COPD: prevalence and clinical characteristics.
Singh D, Kolsum U, Brightling CE, Locantore N, Agusti A, Tal-Singer R; ECLIPSE investigators. Singh D, et al. Among authors: brightling ce. Eur Respir J. 2014 Dec;44(6):1697-700. doi: 10.1183/09031936.00162414. Epub 2014 Oct 16. Eur Respir J. 2014. PMID: 25323230 Free article. No abstract available.
Oxidative stress-induced mitochondrial dysfunction drives inflammation and airway smooth muscle remodeling in patients with chronic obstructive pulmonary disease.
Wiegman CH, Michaeloudes C, Haji G, Narang P, Clarke CJ, Russell KE, Bao W, Pavlidis S, Barnes PJ, Kanerva J, Bittner A, Rao N, Murphy MP, Kirkham PA, Chung KF, Adcock IM; COPDMAP. Wiegman CH, et al. J Allergy Clin Immunol. 2015 Sep;136(3):769-80. doi: 10.1016/j.jaci.2015.01.046. Epub 2015 Mar 29. J Allergy Clin Immunol. 2015. PMID: 25828268 Free PMC article.
Blood and sputum eosinophils in COPD; relationship with bacterial load.
Kolsum U, Donaldson GC, Singh R, Barker BL, Gupta V, George L, Webb AJ, Thurston S, Brookes AJ, McHugh TD, Wedzicha JA, Brightling CE, Singh D. Kolsum U, et al. Among authors: brightling ce. Respir Res. 2017 May 8;18(1):88. doi: 10.1186/s12931-017-0570-5. Respir Res. 2017. PMID: 28482840 Free PMC article.
Impaired Mitochondrial Microbicidal Responses in Chronic Obstructive Pulmonary Disease Macrophages.
Bewley MA, Preston JA, Mohasin M, Marriott HM, Budd RC, Swales J, Collini P, Greaves DR, Craig RW, Brightling CE, Donnelly LE, Barnes PJ, Singh D, Shapiro SD, Whyte MKB, Dockrell DH. Bewley MA, et al. Among authors: brightling ce. Am J Respir Crit Care Med. 2017 Oct 1;196(7):845-855. doi: 10.1164/rccm.201608-1714OC. Am J Respir Crit Care Med. 2017. PMID: 28557543 Free PMC article.
Influence of lung CT changes in chronic obstructive pulmonary disease (COPD) on the human lung microbiome.
Engel M, Endesfelder D, Schloter-Hai B, Kublik S, Granitsiotis MS, Boschetto P, Stendardo M, Barta I, Dome B, Deleuze JF, Boland A, Müller-Quernheim J, Prasse A, Welte T, Hohlfeld J, Subramanian D, Parr D, Gut IG, Greulich T, Koczulla AR, Nowinski A, Gorecka D, Singh D, Gupta S, Brightling CE, Hoffmann H, Frankenberger M, Hofer TP, Burggraf D, Heiss-Neumann M, Ziegler-Heitbrock L, Schloter M, Zu Castell W. Engel M, et al. Among authors: brightling ce. PLoS One. 2017 Jul 13;12(7):e0180859. doi: 10.1371/journal.pone.0180859. eCollection 2017. PLoS One. 2017. PMID: 28704452 Free PMC article.
544 results