Bretner M - Search Results

1

A competition between hydrophobic and electrostatic interactions in protein-ligand systems. Binding of heterogeneously halogenated benzotriazoles by the catalytic subunit of human protein kinase CK2.

Kasperowicz S, Marzec E, Maciejewska AM, Trzybiński D, Bretner M, Woźniak K, Poznański J, Mieczkowska K. Kasperowicz S, et al. Among authors: bretner m. IUBMB Life. 2020 Jun;72(6):1211-1219. doi: 10.1002/iub.2271. Epub 2020 Mar 12. IUBMB Life. 2020. PMID: 32162783 Free article.

2

Thermodynamic parameters for binding of some halogenated inhibitors of human protein kinase CK2.

Winiewska M, Makowska M, Maj P, Wielechowska M, Bretner M, Poznański J, Shugar D. Winiewska M, et al. Among authors: bretner m. Biochem Biophys Res Commun. 2015 Jan 2;456(1):282-7. doi: 10.1016/j.bbrc.2014.11.072. Epub 2014 Nov 25. Biochem Biophys Res Commun. 2015. PMID: 25450618

3

Experimental (13C NMR) and theoretical (ab initio molecular orbital calculations) studies on the prototropic tautomerism of benzotriazole and some derivatives symmetrically substituted on the benzene ring.

Poznański J, Najda A, Bretner M, Shugar D. Poznański J, et al. Among authors: bretner m. J Phys Chem A. 2007 Jul 19;111(28):6501-9. doi: 10.1021/jp071611h. Epub 2007 Jun 22. J Phys Chem A. 2007. PMID: 17585743

4

Synthesis, solution conformation and anti-HIV activity of novel 3'-substituted-2',3'-dideoxy-5-hydroxymethyluridines and their 4,5-substituted analogues.

Poznanski J, Bretner M, Kulikowski T, Balzarini J, Van Aerschot A, De Clercq E. Poznanski J, et al. Among authors: bretner m. Antivir Chem Chemother. 2003 May;14(3):127-38. doi: 10.1177/095632020301400302. Antivir Chem Chemother. 2003. PMID: 14521329 Free article.

5

Human dihydrofolate reductase is a substrate of protein kinase CK2α.

Skierka K, Wilamowski P, Wielechowska M, Cysewski D, Senkara E, Wińska P, Bretner M, Cieśla J. Skierka K, et al. Among authors: bretner m. Biochem Biophys Res Commun. 2019 May 28;513(2):368-373. doi: 10.1016/j.bbrc.2019.03.186. Epub 2019 Apr 5. Biochem Biophys Res Commun. 2019. PMID: 30961929

6

Synthesis of new analogs of benzotriazole, benzimidazole and phthalimide--potential inhibitors of human protein kinase CK2.

Najda-Bernatowicz A, Łebska M, Orzeszko A, Kopańska K, Krzywińska E, Muszyńska G, Bretner M. Najda-Bernatowicz A, et al. Among authors: bretner m. Bioorg Med Chem. 2009 Feb 15;17(4):1573-8. doi: 10.1016/j.bmc.2008.12.071. Epub 2009 Jan 7. Bioorg Med Chem. 2009. PMID: 19168362

7

5-Substituted N(4)-hydroxy-2'-deoxycytidines and their 5'-monophosphates: synthesis, conformation, interaction with tumor thymidylate synthase, and in vitro antitumor activity.

Felczak K, Miazga A, Poznański J, Bretner M, Kulikowski T, Dzik JM, Gołos B, Zieliński Z, Cieśla J, Rode W. Felczak K, et al. Among authors: bretner m. J Med Chem. 2000 Nov 30;43(24):4647-56. doi: 10.1021/jm000975u. J Med Chem. 2000. PMID: 11101356

8

1H NMR conformational study of a variety of alpha-anomers of C5-substituted 2'-deoxyuridines: comparison to their antiherpetic beta counterparts.

Poznański J, Felczak K, Bretner M, Kulikowski T, Remin M. Poznański J, et al. Among authors: bretner m. Biochem Biophys Res Commun. 2001 May 25;283(5):1142-9. doi: 10.1006/bbrc.2001.4921. Biochem Biophys Res Commun. 2001. PMID: 11355892

9

Synthesis, biological properties and structural study of new halogenated azolo[4,5-b]pyridines as inhibitors of CK2 kinase.

Chojnacki K, Lindenblatt D, Wińska P, Wielechowska M, Toelzer C, Niefind K, Bretner M. Chojnacki K, et al. Among authors: bretner m. Bioorg Chem. 2021 Jan;106:104502. doi: 10.1016/j.bioorg.2020.104502. Epub 2020 Nov 24. Bioorg Chem. 2021. PMID: 33317841

10

Synthesis and interactions with thymidylate synthase of 2,4-dithio analogues of dUMP and 5-fluoro-dUMP.

Dzik JM, Bretner M, Kulikowski T, Gołos B, Jarmuła A, Poznański J, Rode W, Shugar D. Dzik JM, et al. Among authors: bretner m. Biochim Biophys Acta. 1996 Mar 7;1293(1):1-8. doi: 10.1016/0167-4838(95)00219-7. Biochim Biophys Acta. 1996. PMID: 8652614

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