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Supramolecular Mechanism of Viral Envelope Disruption by Molecular Tweezers.
Weil T, Groß R, Röcker A, Bravo-Rodriguez K, Heid C, Sowislok A, Le MH, Erwin N, Dwivedi M, Bart SM, Bates P, Wettstein L, Müller JA, Harms M, Sparrer K, Ruiz-Blanco YB, Stürzel CM, von Einem J, Lippold S, Read C, Walther P, Hebel M, Kreppel F, Klärner FG, Bitan G, Ehrmann M, Weil T, Winter R, Schrader T, Shorter J, Sanchez-Garcia E, Münch J. Weil T, et al. Among authors: bravo rodriguez k. J Am Chem Soc. 2020 Oct 7;142(40):17024-17038. doi: 10.1021/jacs.0c06400. Epub 2020 Sep 28. J Am Chem Soc. 2020. PMID: 32926779 Free PMC article.
Molecular tweezers with varying anions: a comparative study.
Dutt S, Wilch C, Gersthagen T, Talbiersky P, Bravo-Rodriguez K, Hanni M, Sánchez-García E, Ochsenfeld C, Klärner FG, Schrader T. Dutt S, et al. J Org Chem. 2013 Jul 5;78(13):6721-34. doi: 10.1021/jo4009673. Epub 2013 Jun 18. J Org Chem. 2013. PMID: 23750919
Inhibition of Huntingtin Exon-1 Aggregation by the Molecular Tweezer CLR01.
Vöpel T, Bravo-Rodriguez K, Mittal S, Vachharajani S, Gnutt D, Sharma A, Steinhof A, Fatoba O, Ellrichmann G, Nshanian M, Heid C, Loo JA, Klärner FG, Schrader T, Bitan G, Wanker EE, Ebbinghaus S, Sanchez-Garcia E. Vöpel T, et al. Among authors: bravo rodriguez k. J Am Chem Soc. 2017 Apr 26;139(16):5640-5643. doi: 10.1021/jacs.6b11039. Epub 2017 Apr 13. J Am Chem Soc. 2017. PMID: 28406616 Free PMC article.
The Molecular Tweezer CLR01 Stabilizes a Disordered Protein-Protein Interface.
Bier D, Mittal S, Bravo-Rodriguez K, Sowislok A, Guillory X, Briels J, Heid C, Bartel M, Wettig B, Brunsveld L, Sanchez-Garcia E, Schrader T, Ottmann C. Bier D, et al. Among authors: bravo rodriguez k. J Am Chem Soc. 2017 Nov 15;139(45):16256-16263. doi: 10.1021/jacs.7b07939. Epub 2017 Nov 2. J Am Chem Soc. 2017. PMID: 29039919 Free PMC article.
An allosteric HTRA1-calpain 2 complex with restricted activation profile.
Rey J, Breiden M, Lux V, Bluemke A, Steindel M, Ripkens K, Möllers B, Bravo Rodriguez K, Boisguerin P, Volkmer R, Mieres-Perez J, Clausen T, Sanchez-Garcia E, Ehrmann M. Rey J, et al. Among authors: bravo rodriguez k. Proc Natl Acad Sci U S A. 2022 Apr 5;119(14):e2113520119. doi: 10.1073/pnas.2113520119. Epub 2022 Mar 29. Proc Natl Acad Sci U S A. 2022. PMID: 35349341 Free PMC article.
27 results