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Supramolecular Mechanism of Viral Envelope Disruption by Molecular Tweezers.
Weil T, Groß R, Röcker A, Bravo-Rodriguez K, Heid C, Sowislok A, Le MH, Erwin N, Dwivedi M, Bart SM, Bates P, Wettstein L, Müller JA, Harms M, Sparrer K, Ruiz-Blanco YB, Stürzel CM, von Einem J, Lippold S, Read C, Walther P, Hebel M, Kreppel F, Klärner FG, Bitan G, Ehrmann M, Weil T, Winter R, Schrader T, Shorter J, Sanchez-Garcia E, Münch J. Weil T, et al. Among authors: bravo rodriguez k. J Am Chem Soc. 2020 Oct 7;142(40):17024-17038. doi: 10.1021/jacs.0c06400. Epub 2020 Sep 28. J Am Chem Soc. 2020. PMID: 32926779 Free PMC article.
A molecular tweezer antagonizes seminal amyloids and HIV infection.
Lump E, Castellano LM, Meier C, Seeliger J, Erwin N, Sperlich B, Stürzel CM, Usmani S, Hammond RM, von Einem J, Gerold G, Kreppel F, Bravo-Rodriguez K, Pietschmann T, Holmes VM, Palesch D, Zirafi O, Weissman D, Sowislok A, Wettig B, Heid C, Kirchhoff F, Weil T, Klärner FG, Schrader T, Bitan G, Sanchez-Garcia E, Winter R, Shorter J, Münch J. Lump E, et al. Elife. 2015 Aug 18;4:e05397. doi: 10.7554/eLife.05397. Elife. 2015. PMID: 26284498 Free PMC article.
Inhibition of Huntingtin Exon-1 Aggregation by the Molecular Tweezer CLR01.
Vöpel T, Bravo-Rodriguez K, Mittal S, Vachharajani S, Gnutt D, Sharma A, Steinhof A, Fatoba O, Ellrichmann G, Nshanian M, Heid C, Loo JA, Klärner FG, Schrader T, Bitan G, Wanker EE, Ebbinghaus S, Sanchez-Garcia E. Vöpel T, et al. Among authors: bravo rodriguez k. J Am Chem Soc. 2017 Apr 26;139(16):5640-5643. doi: 10.1021/jacs.6b11039. Epub 2017 Apr 13. J Am Chem Soc. 2017. PMID: 28406616 Free PMC article.
Molecular tweezers with varying anions: a comparative study.
Dutt S, Wilch C, Gersthagen T, Talbiersky P, Bravo-Rodriguez K, Hanni M, Sánchez-García E, Ochsenfeld C, Klärner FG, Schrader T. Dutt S, et al. J Org Chem. 2013 Jul 5;78(13):6721-34. doi: 10.1021/jo4009673. Epub 2013 Jun 18. J Org Chem. 2013. PMID: 23750919
The Molecular Tweezer CLR01 Stabilizes a Disordered Protein-Protein Interface.
Bier D, Mittal S, Bravo-Rodriguez K, Sowislok A, Guillory X, Briels J, Heid C, Bartel M, Wettig B, Brunsveld L, Sanchez-Garcia E, Schrader T, Ottmann C. Bier D, et al. Among authors: bravo rodriguez k. J Am Chem Soc. 2017 Nov 15;139(45):16256-16263. doi: 10.1021/jacs.7b07939. Epub 2017 Nov 2. J Am Chem Soc. 2017. PMID: 29039919 Free PMC article.
Molecular tweezers modulate 14-3-3 protein-protein interactions.
Bier D, Rose R, Bravo-Rodriguez K, Bartel M, Ramirez-Anguita JM, Dutt S, Wilch C, Klärner FG, Sanchez-Garcia E, Schrader T, Ottmann C. Bier D, et al. Nat Chem. 2013 Mar;5(3):234-9. doi: 10.1038/nchem.1570. Epub 2013 Feb 17. Nat Chem. 2013. PMID: 23422566
27 results