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Trypanocidal agents with low cytotoxicity to mammalian cell line: a comparison of the theoretical and biological features of lapachone derivatives.
Ferreira VF, Jorqueira A, Souza AM, da Silva MN, de Souza MC, Gouvêa RM, Rodrigues CR, Pinto AV, Castro HC, Santos DO, Araújo HP, Bourguignon SC. Ferreira VF, et al. Among authors: bourguignon sc. Bioorg Med Chem. 2006 Aug 15;14(16):5459-66. doi: 10.1016/j.bmc.2006.04.046. Epub 2006 May 24. Bioorg Med Chem. 2006. PMID: 16725327
Epoxy-α-lapachone has in vitro and in vivo anti-leishmania (Leishmania) amazonensis effects and inhibits serine proteinase activity in this parasite.
Souza-Silva F, Bourguignon SC, Pereira BA, Côrtes LM, de Oliveira LF, Henriques-Pons A, Finkelstein LC, Ferreira VF, Carneiro PF, de Pinho RT, Caffarena ER, Alves CR. Souza-Silva F, et al. Among authors: bourguignon sc. Antimicrob Agents Chemother. 2015 Apr;59(4):1910-8. doi: 10.1128/AAC.04742-14. Epub 2015 Jan 12. Antimicrob Agents Chemother. 2015. PMID: 25583728 Free PMC article.
Leishmaniasis treatment--a challenge that remains: a review.
Santos DO, Coutinho CE, Madeira MF, Bottino CG, Vieira RT, Nascimento SB, Bernardino A, Bourguignon SC, Corte-Real S, Pinho RT, Rodrigues CR, Castro HC. Santos DO, et al. Among authors: bourguignon sc. Parasitol Res. 2008 Jun;103(1):1-10. doi: 10.1007/s00436-008-0943-2. Parasitol Res. 2008. PMID: 18389282 Review.
28 results