Boulton ME - Search Results

1

In pursuit of new anti-angiogenic therapies for cancer treatment.

Cai J, Han S, Qing R, Liao D, Law B, Boulton ME. Cai J, et al. Among authors: boulton me. Front Biosci (Landmark Ed). 2011 Jan 1;16(3):803-14. doi: 10.2741/3721. Front Biosci (Landmark Ed). 2011. PMID: 21196204 Free PMC article. Review.

2

αB-crystallin, an effector of unfolded protein response, confers anti-VEGF resistance to breast cancer via maintenance of intracrine VEGF in endothelial cells.

Ruan Q, Han S, Jiang WG, Boulton ME, Chen ZJ, Law BK, Cai J. Ruan Q, et al. Among authors: boulton me. Mol Cancer Res. 2011 Dec;9(12):1632-43. doi: 10.1158/1541-7786.MCR-11-0327. Epub 2011 Oct 7. Mol Cancer Res. 2011. PMID: 21984182 Free PMC article. Retracted.

3

Development of an anti-angiogenic therapeutic model combining scAAV2-delivered siRNAs and noninvasive photoacoustic imaging of tumor vasculature development.

Ruan Q, Xi L, Boye SL, Han S, Chen ZJ, Hauswirth WW, Lewin AS, Boulton ME, Law BK, Jiang WG, Jiang H, Cai J. Ruan Q, et al. Among authors: boulton me. Cancer Lett. 2013 May 10;332(1):120-9. doi: 10.1016/j.canlet.2012.11.016. Epub 2012 Nov 27. Cancer Lett. 2013. PMID: 23196055 Free PMC article.

4

γ-Secretase and presenilin mediate cleavage and phosphorylation of vascular endothelial growth factor receptor-1.

Cai J, Chen Z, Ruan Q, Han S, Liu L, Qi X, Boye SL, Hauswirth WW, Grant MB, Boulton ME. Cai J, et al. Among authors: boulton me. J Biol Chem. 2011 Dec 9;286(49):42514-42523. doi: 10.1074/jbc.M111.296590. Epub 2011 Oct 20. J Biol Chem. 2011. PMID: 22016384 Free PMC article.

5

β-Secretase (BACE1) inhibition causes retinal pathology by vascular dysregulation and accumulation of age pigment.

Cai J, Qi X, Kociok N, Skosyrski S, Emilio A, Ruan Q, Han S, Liu L, Chen Z, Bowes Rickman C, Golde T, Grant MB, Saftig P, Serneels L, de Strooper B, Joussen AM, Boulton ME. Cai J, et al. Among authors: boulton me. EMBO Mol Med. 2012 Sep;4(9):980-91. doi: 10.1002/emmm.201101084. Epub 2012 Aug 20. EMBO Mol Med. 2012. PMID: 22903875 Free PMC article.

6

Targeting the IRE1α/XBP1 and ATF6 arms of the unfolded protein response enhances VEGF blockade to prevent retinal and choroidal neovascularization.

Liu L, Qi X, Chen Z, Shaw L, Cai J, Smith LH, Grant MB, Boulton ME. Liu L, et al. Among authors: boulton me. Am J Pathol. 2013 Apr;182(4):1412-24. doi: 10.1016/j.ajpath.2012.12.020. Epub 2013 Feb 8. Am J Pathol. 2013. PMID: 23395094 Free PMC article.

7

Placenta growth factor-1 exerts time-dependent stabilization of adherens junctions following VEGF-induced vascular permeability.

Cai J, Wu L, Qi X, Shaw L, Li Calzi S, Caballero S, Jiang WG, Vinores SA, Antonetti D, Ahmed A, Grant MB, Boulton ME. Cai J, et al. Among authors: boulton me. PLoS One. 2011 Mar 25;6(3):e18076. doi: 10.1371/journal.pone.0018076. PLoS One. 2011. PMID: 21464949 Free PMC article. Retracted.

8

PEDF regulates vascular permeability by a γ-secretase-mediated pathway.

Cai J, Wu L, Qi X, Li Calzi S, Caballero S, Shaw L, Ruan Q, Grant MB, Boulton ME. Cai J, et al. Among authors: boulton me. PLoS One. 2011;6(6):e21164. doi: 10.1371/journal.pone.0021164. Epub 2011 Jun 17. PLoS One. 2011. PMID: 21695048 Free PMC article.

9

Expression of placenta growth factor is regulated by both VEGF and hyperglycaemia via VEGFR-2.

Zhao B, Cai J, Boulton M. Zhao B, et al. Microvasc Res. 2004 Nov;68(3):239-46. doi: 10.1016/j.mvr.2004.07.004. Microvasc Res. 2004. PMID: 15501243

10

Protection of blood retinal barrier and systemic vasculature by insulin-like growth factor binding protein-3.

Jarajapu YP, Cai J, Yan Y, Li Calzi S, Kielczewski JL, Hu P, Shaw LC, Firth SM, Chan-Ling T, Boulton ME, Baxter RC, Grant MB. Jarajapu YP, et al. Among authors: boulton me. PLoS One. 2012;7(7):e39398. doi: 10.1371/journal.pone.0039398. Epub 2012 Jul 6. PLoS One. 2012. PMID: 22792172 Free PMC article.

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