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ACSL4 and the lipoxygenases 15/15B are pivotal for ferroptosis induced by iron and PUFA dyshomeostasis in dopaminergic neurons.
Free Radic Biol Med. 2023 Feb 1;195:145-157. doi: 10.1016/j.freeradbiomed.2022.12.086. Epub 2022 Dec 26.
Free Radic Biol Med. 2023.
PMID: 36581060
Repositioning of FDA-Approved antifungal agents to interrogate Acyl-CoA synthetase long chain family member 4 (ACSL4) in ferroptosis.
Marteau R, Ravez S, Mazhari Dorooee D, Bouchaoui H, Porte K, Devedjian JC, Melnyk P, Devos D, Frédérick R, El Bakali J.
Marteau R, et al. Among authors: bouchaoui h.
Biochem Pharmacol. 2022 Oct;204:115239. doi: 10.1016/j.bcp.2022.115239. Epub 2022 Sep 6.
Biochem Pharmacol. 2022.
PMID: 36075462
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Alpha synuclein determines ferroptosis sensitivity in dopaminergic neurons via modulation of ether-phospholipid membrane composition.
Mahoney-Sanchez L, Bouchaoui H, Boussaad I, Jonneaux A, Timmerman K, Berdeaux O, Ayton S, Krüger R, Duce JA, Devos D, Devedjian JC.
Mahoney-Sanchez L, et al. Among authors: bouchaoui h.
Cell Rep. 2022 Aug 23;40(8):111231. doi: 10.1016/j.celrep.2022.111231.
Cell Rep. 2022.
PMID: 36001957
Free article.
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Ferroptosis and its potential role in the physiopathology of Parkinson's Disease.
Mahoney-Sánchez L, Bouchaoui H, Ayton S, Devos D, Duce JA, Devedjian JC.
Mahoney-Sánchez L, et al. Among authors: bouchaoui h.
Prog Neurobiol. 2021 Jan;196:101890. doi: 10.1016/j.pneurobio.2020.101890. Epub 2020 Jul 26.
Prog Neurobiol. 2021.
PMID: 32726602
Free article.
Review.
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Conservative iron chelation for neurodegenerative diseases such as Parkinson's disease and amyotrophic lateral sclerosis.
Devos D, Cabantchik ZI, Moreau C, Danel V, Mahoney-Sanchez L, Bouchaoui H, Gouel F, Rolland AS, Duce JA, Devedjian JC; FAIRPARK-II and FAIRALS-II studygroups.
Devos D, et al. Among authors: bouchaoui h.
J Neural Transm (Vienna). 2020 Feb;127(2):189-203. doi: 10.1007/s00702-019-02138-1. Epub 2020 Jan 7.
J Neural Transm (Vienna). 2020.
PMID: 31912279
Free article.
Review.
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