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Safety and efficacy of mitapivat, an oral pyruvate kinase activator, in sickle cell disease: A phase 2, open-label study.
van Dijk MJ, Rab MAE, van Oirschot BA, Bos J, Derichs C, Rijneveld AW, Cnossen MH, Nur E, Biemond BJ, Bartels M, Jans JJM, van Solinge WW, Schutgens REG, van Wijk R, van Beers EJ. van Dijk MJ, et al. Among authors: bos j. Am J Hematol. 2022 Jul;97(7):E226-E229. doi: 10.1002/ajh.26554. Epub 2022 Apr 16. Am J Hematol. 2022. PMID: 35384026 Free article. Clinical Trial. No abstract available.
Rapid and reproducible characterization of sickling during automated deoxygenation in sickle cell disease patients.
Rab MAE, van Oirschot BA, Bos J, Merkx TH, van Wesel ACW, Abdulmalik O, Safo MK, Versluijs BA, Houwing ME, Cnossen MH, Riedl J, Schutgens REG, Pasterkamp G, Bartels M, van Beers EJ, van Wijk R. Rab MAE, et al. Among authors: bos j. Am J Hematol. 2019 May;94(5):575-584. doi: 10.1002/ajh.25443. Epub 2019 Mar 8. Am J Hematol. 2019. PMID: 30784099 Free PMC article.
Oxygen gradient ektacytometry-derived biomarkers are associated with vaso-occlusive crises and correlate with treatment response in sickle cell disease.
Rab MAE, Kanne CK, Bos J, van Oirschot BA, Boisson C, Houwing ME, Gerritsma J, Teske E, Renoux C, Riedl J, Schutgens REG, Bartels M, Nur E, Joly P, Fort R, Cnossen MH, van Wijk R, Connes P, van Beers EJ, Sheehan VA. Rab MAE, et al. Among authors: bos j. Am J Hematol. 2021 Jan;96(1):E29-E32. doi: 10.1002/ajh.26031. Epub 2020 Nov 11. Am J Hematol. 2021. PMID: 33095451 Free PMC article. No abstract available.
Ektacytometry Analysis of Post-splenectomy Red Blood Cell Properties Identifies Cell Membrane Stability Test as a Novel Biomarker of Membrane Health in Hereditary Spherocytosis.
Berrevoets MC, Bos J, Huisjes R, Merkx TH, van Oirschot BA, van Solinge WW, Verweij JW, Lindeboom MYA, van Beers EJ, Bartels M, van Wijk R, Rab MAE. Berrevoets MC, et al. Among authors: bos j. Front Physiol. 2021 Mar 25;12:641384. doi: 10.3389/fphys.2021.641384. eCollection 2021. Front Physiol. 2021. PMID: 33841180 Free PMC article.
Effects of Genotypes and Treatment on Oxygenscan Parameters in Sickle Cell Disease.
Boisson C, Rab MAE, Nader E, Renoux C, Kanne C, Bos J, van Oirschot BA, Joly P, Fort R, Gauthier A, Stauffer E, Poutrel S, Kebaili K, Cannas G, Garnier N, Renard C, Hequet O, Hot A, Bertrand Y, van Wijk R, Sheehan VA, van Beers EJ, Connes P. Boisson C, et al. Among authors: bos j. Cells. 2021 Apr 5;10(4):811. doi: 10.3390/cells10040811. Cells. 2021. PMID: 33916502 Free PMC article.
A novel missense variant in ATP11C is associated with reduced red blood cell phosphatidylserine flippase activity and mild hereditary hemolytic anemia.
van Dijk MJ, van Oirschot BA, Harrison AN, Recktenwald SM, Qiao M, Stommen A, Cloos AS, Vanderroost J, Terrasi R, Dey K, Bos J, Rab MAE, Bogdanova A, Minetti G, Muccioli GG, Tyteca D, Egée S, Kaestner L, Molday RS, van Beers EJ, van Wijk R. van Dijk MJ, et al. Among authors: bos j. Am J Hematol. 2023 Dec;98(12):1877-1887. doi: 10.1002/ajh.27088. Epub 2023 Sep 6. Am J Hematol. 2023. PMID: 37671681
One-year safety and efficacy of mitapivat in sickle cell disease: follow-up results of a phase 2, open-label study.
van Dijk MJ, Rab MAE, van Oirschot BA, Bos J, Derichs C, Rijneveld AW, Cnossen MH, Nur E, Biemond BJ, Bartels M, Jans JJM, van Solinge WW, Schutgens REG, van Wijk R, van Beers EJ. van Dijk MJ, et al. Among authors: bos j. Blood Adv. 2023 Dec 26;7(24):7539-7550. doi: 10.1182/bloodadvances.2023011477. Blood Adv. 2023. PMID: 37934880 Free PMC article. Clinical Trial.
1,413 results