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Inactivation of CK1α in multiple myeloma empowers drug cytotoxicity by affecting AKT and β-catenin survival signaling pathways.
Manni S, Carrino M, Manzoni M, Gianesin K, Nunes SC, Costacurta M, Tubi LQ, Macaccaro P, Taiana E, Cabrelle A, Barilà G, Martines A, Zambello R, Bonaldi L, Trentin L, Neri A, Semenzato G, Piazza F. Manni S, et al. Among authors: bonaldi l. Oncotarget. 2017 Feb 28;8(9):14604-14619. doi: 10.18632/oncotarget.14654. Oncotarget. 2017. PMID: 28099937 Free PMC article.
Telomere length and telomerase levels delineate subgroups of B-cell chronic lymphocytic leukemia with different biological characteristics and clinical outcomes.
Rampazzo E, Bonaldi L, Trentin L, Visco C, Keppel S, Giunco S, Frezzato F, Facco M, Novella E, Giaretta I, Del Bianco P, Semenzato G, De Rossi A. Rampazzo E, et al. Among authors: bonaldi l. Haematologica. 2012 Jan;97(1):56-63. doi: 10.3324/haematol.2011.049874. Epub 2011 Sep 20. Haematologica. 2012. PMID: 21933855 Free PMC article.
Inhibition of protein kinase CK2 with the clinical-grade small ATP-competitive compound CX-4945 or by RNA interference unveils its role in acute myeloid leukemia cell survival, p53-dependent apoptosis and daunorubicin-induced cytotoxicity.
Quotti Tubi L, Gurrieri C, Brancalion A, Bonaldi L, Bertorelle R, Manni S, Pavan L, Lessi F, Zambello R, Trentin L, Adami F, Ruzzene M, Pinna LA, Semenzato G, Piazza F. Quotti Tubi L, et al. Among authors: bonaldi l. J Hematol Oncol. 2013 Oct 12;6:78. doi: 10.1186/1756-8722-6-78. J Hematol Oncol. 2013. PMID: 24283803 Free PMC article.
Cytogenetic Impact on Lenalidomide Treatment in Relapsed/Refractory Multiple Myeloma: A Real-Life Evaluation.
Zambello R, Bonaldi L, Berno T, Martines A, Sechettin E, De March E, Branca A, Lico A, Minotto C, Briani C, Gurrieri C, Temporin F, Battistutta C, Piazza F, Cavraro M, Trentin L, Semenzato G. Zambello R, et al. Among authors: bonaldi l. Clin Lymphoma Myeloma Leuk. 2015 Oct;15(10):592-8. doi: 10.1016/j.clml.2015.05.003. Epub 2015 Jun 6. Clin Lymphoma Myeloma Leuk. 2015. PMID: 26141212
Integrated CLL Scoring System, a New and Simple Index to Predict Time to Treatment and Overall Survival in Patients With Chronic Lymphocytic Leukemia.
Visentin A, Facco M, Frezzato F, Castelli M, Trimarco V, Martini V, Gattazzo C, Severin F, Chiodin G, Martines A, Bonaldi L, Gianesello I, Pagnin E, Boscaro E, Piazza F, Zambello R, Semenzato G, Trentin L. Visentin A, et al. Among authors: bonaldi l. Clin Lymphoma Myeloma Leuk. 2015 Oct;15(10):612-20.e1-5. doi: 10.1016/j.clml.2015.06.001. Epub 2015 Jun 20. Clin Lymphoma Myeloma Leuk. 2015. PMID: 26233718
In chronic lymphocytic leukaemia with complex karyotype, major structural abnormalities identify a subset of patients with inferior outcome and distinct biological characteristics.
Rigolin GM, Saccenti E, Guardalben E, Cavallari M, Formigaro L, Zagatti B, Visentin A, Mauro FR, Lista E, Bassi C, Lupini L, Quaglia FM, Urso A, Bardi MA, Bonaldi L, Volta E, Tammiso E, Ilari C, Cafforio L, Melandri A, Cavazzini F, Negrini M, Semenzato G, Trentin L, Foà R, Cuneo A. Rigolin GM, et al. Among authors: bonaldi l. Br J Haematol. 2018 Apr;181(2):229-233. doi: 10.1111/bjh.15174. Epub 2018 Apr 2. Br J Haematol. 2018. PMID: 29611195 Free article.
BCR kinase inhibitors, idelalisib and ibrutinib, are active and effective in Richter syndrome.
Visentin A, Imbergamo S, Scomazzon E, Pravato S, Frezzato F, Bonaldi L, Pizzi M, Vio S, Gregianin M, Burei M, Facco M, Semenzato G, Piazza F, Trentin L. Visentin A, et al. Among authors: bonaldi l. Br J Haematol. 2019 Apr;185(1):193-197. doi: 10.1111/bjh.15440. Epub 2018 Jul 5. Br J Haematol. 2019. PMID: 29974955 Free article. No abstract available.
69 results