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An attempt to chemically state the cross-talk between monomers of COX homodimers by double/hybrid inhibitors mofezolac-spacer-mofezolac and mofezolac-spacer-arachidonic acid.
Perrone MG, Miciaccia M, Vitale P, Ferorelli S, Araújo CDCB, de Almeida GS, Souza Domingos TF, da Silva LCRP, de Pádula M, Cabral LM, Sathler PC, Bonaccorso C, Fortuna CG, Scilimati A. Perrone MG, et al. Among authors: bonaccorso c. Eur J Med Chem. 2021 Jan 1;209:112919. doi: 10.1016/j.ejmech.2020.112919. Epub 2020 Oct 9. Eur J Med Chem. 2021. PMID: 33129592
New linezolid-like 1,2,4-oxadiazoles active against Gram-positive multiresistant pathogens.
Fortuna CG, Bonaccorso C, Bulbarelli A, Caltabiano G, Rizzi L, Goracci L, Musumarra G, Pace A, Palumbo Piccionello A, Guarcello A, Pierro P, Cocuzza CE, Musumeci R. Fortuna CG, et al. Among authors: bonaccorso c. Eur J Med Chem. 2013 Jul;65:533-45. doi: 10.1016/j.ejmech.2013.03.069. Epub 2013 May 14. Eur J Med Chem. 2013. PMID: 23811204
New potent antibacterials against Gram-positive multiresistant pathogens: effects of side chain modification and chirality in linezolid-like 1,2,4-oxadiazoles.
Fortuna CG, Berardozzi R, Bonaccorso C, Caltabiano G, Di Bari L, Goracci L, Guarcello A, Pace A, Palumbo Piccionello A, Pescitelli G, Pierro P, Lonati E, Bulbarelli A, Cocuzza CE, Musumarra G, Musumeci R. Fortuna CG, et al. Among authors: bonaccorso c. Bioorg Med Chem. 2014 Dec 15;22(24):6814-25. doi: 10.1016/j.bmc.2014.10.037. Epub 2014 Nov 1. Bioorg Med Chem. 2014. PMID: 25464880
62 results