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TRPV6 calcium channel translocates to the plasma membrane via Orai1-mediated mechanism and controls cancer cell survival.
Raphaël M, Lehen'kyi V, Vandenberghe M, Beck B, Khalimonchyk S, Vanden Abeele F, Farsetti L, Germain E, Bokhobza A, Mihalache A, Gosset P, Romanin C, Clézardin P, Skryma R, Prevarskaya N. Raphaël M, et al. Among authors: bokhobza a. Proc Natl Acad Sci U S A. 2014 Sep 16;111(37):E3870-9. doi: 10.1073/pnas.1413409111. Epub 2014 Aug 29. Proc Natl Acad Sci U S A. 2014. PMID: 25172921 Free PMC article.
Targeting of short TRPM8 isoforms induces 4TM-TRPM8-dependent apoptosis in prostate cancer cells.
Bidaux G, Borowiec AS, Dubois C, Delcourt P, Schulz C, Vanden Abeele F, Lepage G, Desruelles E, Bokhobza A, Dewailly E, Slomianny C, Roudbaraki M, Héliot L, Bonnal JL, Mauroy B, Mariot P, Lemonnier L, Prevarskaya N. Bidaux G, et al. Among authors: bokhobza a. Oncotarget. 2016 May 17;7(20):29063-80. doi: 10.18632/oncotarget.8666. Oncotarget. 2016. PMID: 27074561 Free PMC article.
Activation of mutated TRPA1 ion channel by resveratrol in human prostate cancer associated fibroblasts (CAF).
Vancauwenberghe E, Noyer L, Derouiche S, Lemonnier L, Gosset P, Sadofsky LR, Mariot P, Warnier M, Bokhobza A, Slomianny C, Mauroy B, Bonnal JL, Dewailly E, Delcourt P, Allart L, Desruelles E, Prevarskaya N, Roudbaraki M. Vancauwenberghe E, et al. Among authors: bokhobza a. Mol Carcinog. 2017 Aug;56(8):1851-1867. doi: 10.1002/mc.22642. Epub 2017 May 22. Mol Carcinog. 2017. PMID: 28277613 Free article.
NALCN-mediated sodium influx confers metastatic prostate cancer cell invasiveness.
Folcher A, Gordienko D, Iamshanova O, Bokhobza A, Shapovalov G, Kannancheri-Puthooru D, Mariot P, Allart L, Desruelles E, Spriet C, Diez R, Oullier T, Marionneau-Lambot S, Brisson L, Geraci S, Impheng H, Lehen'kyi V, Haustrate A, Mihalache A, Gosset P, Chadet S, Retif S, Laube M, Sobilo J, Lerondel S, Villari G, Serini G, Pla AF, Roger S, Fromont-Hankard G, Djamgoz M, Clezardin P, Monteil A, Prevarskaya N. Folcher A, et al. Among authors: bokhobza a. EMBO J. 2023 Jul 3;42(13):e112198. doi: 10.15252/embj.2022112198. Epub 2023 Jun 6. EMBO J. 2023. PMID: 37278161 Free PMC article.
TRP channel-associated factors are a novel protein family that regulates TRPM8 trafficking and activity.
Gkika D, Lemonnier L, Shapovalov G, Gordienko D, Poux C, Bernardini M, Bokhobza A, Bidaux G, Degerny C, Verreman K, Guarmit B, Benahmed M, de Launoit Y, Bindels RJ, Fiorio Pla A, Prevarskaya N. Gkika D, et al. Among authors: bokhobza a. J Cell Biol. 2015 Jan 5;208(1):89-107. doi: 10.1083/jcb.201402076. J Cell Biol. 2015. PMID: 25559186 Free PMC article.
TRPM8 inhibits endothelial cell migration via a non-channel function by trapping the small GTPase Rap1.
Genova T, Grolez GP, Camillo C, Bernardini M, Bokhobza A, Richard E, Scianna M, Lemonnier L, Valdembri D, Munaron L, Philips MR, Mattot V, Serini G, Prevarskaya N, Gkika D, Pla AF. Genova T, et al. Among authors: bokhobza a. J Cell Biol. 2017 Jul 3;216(7):2107-2130. doi: 10.1083/jcb.201506024. Epub 2017 May 26. J Cell Biol. 2017. PMID: 28550110 Free PMC article.
Cold/menthol TRPM8 receptors initiate the cold-shock response and protect germ cells from cold-shock-induced oxidation.
Borowiec AS, Sion B, Chalmel F, D Rolland A, Lemonnier L, De Clerck T, Bokhobza A, Derouiche S, Dewailly E, Slomianny C, Mauduit C, Benahmed M, Roudbaraki M, Jégou B, Prevarskaya N, Bidaux G. Borowiec AS, et al. Among authors: bokhobza a. FASEB J. 2016 Sep;30(9):3155-70. doi: 10.1096/fj.201600257R. Epub 2016 Jun 17. FASEB J. 2016. PMID: 27317670 Free PMC article.
12 results