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Discovery of tetrahydro-cyclopenta[b]indole as selective LXRs modulator.
Ratni H, Blum-Kaelin D, Dehmlow H, Hartman P, Jablonski P, Masciadri R, Maugeais C, Patiny-Adam A, Panday N, Wright M. Ratni H, et al. Among authors: blum kaelin d. Bioorg Med Chem Lett. 2009 Mar 15;19(6):1654-7. doi: 10.1016/j.bmcl.2009.01.109. Epub 2009 Feb 6. Bioorg Med Chem Lett. 2009. PMID: 19231176
Modulating cholesteryl ester transfer protein activity maintains efficient pre-β-HDL formation and increases reverse cholesterol transport.
Niesor EJ, Magg C, Ogawa N, Okamoto H, von der Mark E, Matile H, Schmid G, Clerc RG, Chaput E, Blum-Kaelin D, Huber W, Thoma R, Pflieger P, Kakutani M, Takahashi D, Dernick G, Maugeais C. Niesor EJ, et al. Among authors: blum kaelin d. J Lipid Res. 2010 Dec;51(12):3443-54. doi: 10.1194/jlr.M008706. Epub 2010 Sep 22. J Lipid Res. 2010. PMID: 20861162 Free PMC article.