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Gain-of-function mutation in ubiquitin-ligase KLHL24 causes desmin degradation and dilatation in hiPSC-derived engineered heart tissues.
Vermeer MC, Bolling MC, Bliley JM, Arevalo Gomez KF, Pavez-Giani MG, Kramer D, Romero-Herrera PH, Westenbrink BD, Diercks GF, van den Berg MP, Feinberg AW, Silljé HHW, van der Meer P. Vermeer MC, et al. Among authors: bliley jm. J Clin Invest. 2021 Jul 22;131(17):e140615. doi: 10.1172/JCI140615. Online ahead of print. J Clin Invest. 2021. PMID: 34292882 Free PMC article.
3D bioprinting of collagen to rebuild components of the human heart.
Lee A, Hudson AR, Shiwarski DJ, Tashman JW, Hinton TJ, Yerneni S, Bliley JM, Campbell PG, Feinberg AW. Lee A, et al. Among authors: bliley jm. Science. 2019 Aug 2;365(6452):482-487. doi: 10.1126/science.aav9051. Science. 2019. PMID: 31371612
Dynamic loading of human engineered heart tissue enhances contractile function and drives a desmosome-linked disease phenotype.
Bliley JM, Vermeer MCSC, Duffy RM, Batalov I, Kramer D, Tashman JW, Shiwarski DJ, Lee A, Teplenin AS, Volkers L, Coffin B, Hoes MF, Kalmykov A, Palchesko RN, Sun Y, Jongbloed JDH, Bomer N, de Boer RA, Suurmeijer AJH, Pijnappels DA, Bolling MC, van der Meer P, Feinberg AW. Bliley JM, et al. Sci Transl Med. 2021 Jul 21;13(603):eabd1817. doi: 10.1126/scitranslmed.abd1817. Sci Transl Med. 2021. PMID: 34290054
30 results