3D-bioprinted human tissue and the path toward clinical translation

Jacqueline M Bliley; Daniel J Shiwarski; Adam W Feinberg

doi:10.1126/scitranslmed.abo7047

3D-bioprinted human tissue and the path toward clinical translation

Sci Transl Med. 2022 Oct 12;14(666):eabo7047. doi: 10.1126/scitranslmed.abo7047. Epub 2022 Oct 12.

Authors

Jacqueline M Bliley¹, Daniel J Shiwarski¹, Adam W Feinberg^{1

2}

Affiliations

¹ Department of Biomedical Engineering, Carnegie Mellon University, Pittsburgh, PA 15213, USA.
² Department of Materials Science and Engineering, Carnegie Mellon University, Pittsburgh, PA 15213, USA.

PMID: 36223452
DOI: 10.1126/scitranslmed.abo7047

Abstract

Three-dimensional (3D) bioprinting is a transformative technology for engineering tissues for disease modeling and drug screening and building tissues and organs for repair, regeneration, and replacement. In this Viewpoint, we discuss technological advances in 3D bioprinting, key remaining challenges, and essential milestones toward clinical translation.

Publication types

Review
Research Support, Non-U.S. Gov't
Research Support, U.S. Gov't, P.H.S.
Research Support, N.I.H., Extramural

MeSH terms

Bioprinting* / methods
Drug Evaluation, Preclinical
Humans
Printing, Three-Dimensional*
Tissue Engineering / methods
Tissue Scaffolds

Abstract

Publication types

MeSH terms

Grants and funding