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Development of CAR T-cell lymphoma in 2 of 10 patients effectively treated with piggyBac-modified CD19 CAR T cells.
Bishop DC, Clancy LE, Simms R, Burgess J, Mathew G, Moezzi L, Street JA, Sutrave G, Atkins E, McGuire HM, Gloss BS, Lee K, Jiang W, Maddock K, McCaughan G, Avdic S, Antonenas V, O'Brien TA, Shaw PJ, Irving DO, Gottlieb DJ, Blyth E, Micklethwaite KP. Bishop DC, et al. Blood. 2021 Oct 21;138(16):1504-1509. doi: 10.1182/blood.2021010813. Blood. 2021. PMID: 34010392 Free article. Clinical Trial. No abstract available.
Long-term control of recurrent or refractory viral infections after allogeneic HSCT with third-party virus-specific T cells.
Withers B, Blyth E, Clancy LE, Yong A, Fraser C, Burgess J, Simms R, Brown R, Kliman D, Dubosq MC, Bishop D, Sutrave G, Ma CKK, Shaw PJ, Micklethwaite KP, Gottlieb DJ. Withers B, et al. Blood Adv. 2017 Nov 2;1(24):2193-2205. doi: 10.1182/bloodadvances.2017010223. eCollection 2017 Nov 14. Blood Adv. 2017. PMID: 29296867 Free PMC article.
Prophylactic antigen-specific T-cells targeting seven viral and fungal pathogens after allogeneic haemopoietic stem cell transplant.
Gottlieb DJ, Clancy LE, Withers B, McGuire HM, Luciani F, Singh M, Hughes B, Gloss B, Kliman D, Ma CKK, Panicker S, Bishop D, Dubosq MC, Li Z, Avdic S, Micklethwaite K, Blyth E. Gottlieb DJ, et al. Clin Transl Immunology. 2021 Mar 15;10(3):e1249. doi: 10.1002/cti2.1249. eCollection 2021. Clin Transl Immunology. 2021. PMID: 33747509 Free PMC article.
Investigation of product-derived lymphoma following infusion of piggyBac-modified CD19 chimeric antigen receptor T cells.
Micklethwaite KP, Gowrishankar K, Gloss BS, Li Z, Street JA, Moezzi L, Mach MA, Sutrave G, Clancy LE, Bishop DC, Louie RHY, Cai C, Foox J, MacKay M, Sedlazeck FJ, Blombery P, Mason CE, Luciani F, Gottlieb DJ, Blyth E. Micklethwaite KP, et al. Among authors: bishop dc. Blood. 2021 Oct 21;138(16):1391-1405. doi: 10.1182/blood.2021010858. Blood. 2021. PMID: 33974080 Free PMC article. Clinical Trial.
Combining CD34+ stem cell selection with prophylactic pathogen and leukemia directed T-cell immunotherapy to simultaneously reduce graft versus host disease, infection, and leukemia recurrence after allogeneic stem cell transplant.
Gottlieb DJ, Sutrave G, Jiang W, Avdic S, Street JA, Simms R, Clancy LE, Antonenas V, Gloss BS, Bateman C, Bishop DC, Micklethwaite KP, Blyth E. Gottlieb DJ, et al. Among authors: bishop dc. Am J Hematol. 2023 Jan;98(1):159-165. doi: 10.1002/ajh.26594. Epub 2022 May 20. Am J Hematol. 2023. PMID: 35560045 Free PMC article.
CAR+ and CAR- T cells share a differentiation trajectory into an NK-like subset after CD19 CAR T cell infusion in patients with B cell malignancies.
Louie RHY, Cai C, Samir J, Singh M, Deveson IW, Ferguson JM, Amos TG, McGuire HM, Gowrishankar K, Adikari T, Balderas R, Bonomi M, Ruella M, Bishop D, Gottlieb D, Blyth E, Micklethwaite K, Luciani F. Louie RHY, et al. Nat Commun. 2023 Nov 27;14(1):7767. doi: 10.1038/s41467-023-43656-7. Nat Commun. 2023. PMID: 38012187 Free PMC article.
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