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Tension directly stabilizes reconstituted kinetochore-microtubule attachments.
Akiyoshi B, Sarangapani KK, Powers AF, Nelson CR, Reichow SL, Arellano-Santoyo H, Gonen T, Ranish JA, Asbury CL, Biggins S. Akiyoshi B, et al. Among authors: biggins s. Nature. 2010 Nov 25;468(7323):576-9. doi: 10.1038/nature09594. Nature. 2010. PMID: 21107429 Free PMC article.
Measuring kinetochore-microtubule interaction in vitro.
Driver JW, Powers AF, Sarangapani KK, Biggins S, Asbury CL. Driver JW, et al. Among authors: biggins s. Methods Enzymol. 2014;540:321-37. doi: 10.1016/B978-0-12-397924-7.00018-2. Methods Enzymol. 2014. PMID: 24630115 Free PMC article.
Sister kinetochores are mechanically fused during meiosis I in yeast.
Sarangapani KK, Duro E, Deng Y, Alves Fde L, Ye Q, Opoku KN, Ceto S, Rappsilber J, Corbett KD, Biggins S, Marston AL, Asbury CL. Sarangapani KK, et al. Among authors: biggins s. Science. 2014 Oct 10;346(6206):248-51. doi: 10.1126/science.1256729. Epub 2014 Sep 11. Science. 2014. PMID: 25213378 Free PMC article.
Autophosphorylation is sufficient to release Mps1 kinase from native kinetochores.
Koch LB, Opoku KN, Deng Y, Barber A, Littleton AJ, London N, Biggins S, Asbury CL. Koch LB, et al. Among authors: biggins s. Proc Natl Acad Sci U S A. 2019 Aug 27;116(35):17355-17360. doi: 10.1073/pnas.1901653116. Epub 2019 Aug 12. Proc Natl Acad Sci U S A. 2019. PMID: 31405987 Free PMC article.
Kinetochore-associated Stu2 promotes chromosome biorientation in vivo.
Miller MP, Evans RK, Zelter A, Geyer EA, MacCoss MJ, Rice LM, Davis TN, Asbury CL, Biggins S. Miller MP, et al. Among authors: biggins s. PLoS Genet. 2019 Oct 4;15(10):e1008423. doi: 10.1371/journal.pgen.1008423. eCollection 2019 Oct. PLoS Genet. 2019. PMID: 31584935 Free PMC article.
212 results