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Irreversible inhibition of TRF2TRFH recruiting functions by a covalent cyclic peptide induces telomeric replication stress in cancer cells.
Sobinoff AP, Di Maro S, Low RRJ, Benedetti R, Tomassi S, D'Aniello A, Russo R, Baglivo I, Chianese U, Pedone PV, Chambery A, Cesare AJ, Altucci L, Pickett HA, Cosconati S. Sobinoff AP, et al. Among authors: benedetti r. Cell Chem Biol. 2023 Dec 21;30(12):1652-1665.e6. doi: 10.1016/j.chembiol.2023.11.008. Epub 2023 Dec 7. Cell Chem Biol. 2023. PMID: 38065101
Trials with 'epigenetic' drugs: an update.
Nebbioso A, Carafa V, Benedetti R, Altucci L. Nebbioso A, et al. Among authors: benedetti r. Mol Oncol. 2012 Dec;6(6):657-82. doi: 10.1016/j.molonc.2012.09.004. Epub 2012 Oct 6. Mol Oncol. 2012. PMID: 23103179 Free PMC article. Review.
tert-Butylcarbamate-containing histone deacetylase inhibitors: apoptosis induction, cytodifferentiation, and antiproliferative activities in cancer cells.
Valente S, Trisciuoglio D, Tardugno M, Benedetti R, Labella D, Secci D, Mercurio C, Boggio R, Tomassi S, Di Maro S, Novellino E, Altucci L, Del Bufalo D, Mai A, Cosconati S. Valente S, et al. Among authors: benedetti r. ChemMedChem. 2013 May;8(5):800-11. doi: 10.1002/cmdc.201300005. Epub 2013 Mar 25. ChemMedChem. 2013. PMID: 23526814
Targeting Histone Deacetylases in Diseases: Where Are We?
Benedetti R, Conte M, Altucci L. Benedetti R, et al. Antioxid Redox Signal. 2015 Jul 1;23(1):99-126. doi: 10.1089/ars.2013.5776. Epub 2014 Mar 6. Antioxid Redox Signal. 2015. PMID: 24382114 Free PMC article. Review.
Breast Cancer Vaccines: New Insights.
Benedetti R, Dell'Aversana C, Giorgio C, Astorri R, Altucci L. Benedetti R, et al. Front Endocrinol (Lausanne). 2017 Oct 13;8:270. doi: 10.3389/fendo.2017.00270. eCollection 2017. Front Endocrinol (Lausanne). 2017. PMID: 29081765 Free PMC article. Review.
I BET on anti-FGFR to fight cancer resistance.
Benedetti R, Altucci L. Benedetti R, et al. EMBO Mol Med. 2019 Feb;11(2):e10116. doi: 10.15252/emmm.201810116. EMBO Mol Med. 2019. PMID: 30610114 Free PMC article.
L. Altucci and R. Benedetti discuss the study by Chua et al (in this issue of EMBO Molecular Medicine), in which co-targeting of FGFR signaling increases the responses of metastatic uveal melanoma to BET inhibitors. ...
L. Altucci and R. Benedetti discuss the study by Chua et al (in this issue of EMBO Molecular Medicine), in which co-targeting …
Inhibition of Histone Demethylases LSD1 and UTX Regulates ERα Signaling in Breast Cancer.
Benedetti R, Dell'Aversana C, De Marchi T, Rotili D, Liu NQ, Novakovic B, Boccella S, Di Maro S, Cosconati S, Baldi A, Niméus E, Schultz J, Höglund U, Maione S, Papulino C, Chianese U, Iovino F, Federico A, Mai A, Stunnenberg HG, Nebbioso A, Altucci L. Benedetti R, et al. Cancers (Basel). 2019 Dec 16;11(12):2027. doi: 10.3390/cancers11122027. Cancers (Basel). 2019. PMID: 31888209 Free PMC article.
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