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Synthesis, 123I-Radiolabeling Optimization, and Initial Preclinical Evaluation of Novel Urea-Based PSMA Inhibitors with a Tributylstannyl Prosthetic Group in Their Structures.
Hasnowo LA, Larkina MS, Plotnikov E, Bodenko V, Yuldasheva F, Stasyuk E, Petrov SA, Zyk NY, Machulkin AE, Vorozhtsov NI, Beloglazkina EK, Nenajdenko VG, Tolmachev V, Orlova A, Majouga AG, Yusubov MS. Hasnowo LA, et al. Among authors: beloglazkina ek. Int J Mol Sci. 2023 Jul 30;24(15):12206. doi: 10.3390/ijms241512206. Int J Mol Sci. 2023. PMID: 37569582 Free PMC article.
The Importance of Linkers in the Structure of PSMA Ligands.
Uspenskaya AA, Nimenko EA, Machulkin AE, Beloglazkina EK, Majouga AG. Uspenskaya AA, et al. Among authors: beloglazkina ek. Curr Med Chem. 2022;29(2):268-298. doi: 10.2174/0929867328666210804092200. Curr Med Chem. 2022. PMID: 34348608 Review.
Synthesis and initial in vitro evaluation of PSMA-targeting ligands with a modified aromatic moiety at the lysine ε-nitrogen atom.
Zyk NY, Ber AP, Nimenko EA, Shafikov RR, Evteev SA, Petrov SA, Uspenskaya AA, Dashkova NS, Ivanenkov YA, Skvortsov DA, Beloglazkina EK, Majouga AG, Machulkin AE. Zyk NY, et al. Among authors: beloglazkina ek. Bioorg Med Chem Lett. 2022 Sep 1;71:128840. doi: 10.1016/j.bmcl.2022.128840. Epub 2022 May 31. Bioorg Med Chem Lett. 2022. PMID: 35661685
Synthesis of Prostate-Specific Membrane Antigen-Targeted Bimodal Conjugates of Cytotoxic Agents and Antiandrogens and Their Comparative Assessment with Monoconjugates.
Zyk NY, Garanina AS, Plotnikova EA, Ber AP, Nimenko EA, Dashkova NS, Uspenskaia AA, Shafikov RR, Skvortsov DA, Petrov SA, Pankratov AA, Zyk NV, Majouga AG, Beloglazkina EK, Machulkin AE. Zyk NY, et al. Among authors: beloglazkina ek. Int J Mol Sci. 2023 Jul 11;24(14):11327. doi: 10.3390/ijms241411327. Int J Mol Sci. 2023. PMID: 37511087 Free PMC article.
Synthesis and biological evaluation of Doxorubicin-containing conjugate targeting PSMA.
Ivanenkov YA, Machulkin AE, Garanina AS, Skvortsov DA, Uspenskaya AA, Deyneka EV, Trofimenko AV, Beloglazkina EK, Zyk NV, Koteliansky VE, Bezrukov DS, Aladinskaya AV, Vorobyeva NS, Puchinina MM, Riabykh GK, Sofronova AA, Malyshev AS, Majouga AG. Ivanenkov YA, et al. Among authors: beloglazkina ek. Bioorg Med Chem Lett. 2019 May 15;29(10):1246-1255. doi: 10.1016/j.bmcl.2019.01.040. Epub 2019 Feb 1. Bioorg Med Chem Lett. 2019. PMID: 30904185
Polypeptide-Based Molecular Platform and Its Docetaxel/Sulfo-Cy5-Containing Conjugate for Targeted Delivery to Prostate Specific Membrane Antigen.
Petrov SA, Machulkin AE, Uspenskaya AA, Zyk NY, Nimenko EA, Garanina AS, Petrov RA, Polshakov VI, Grishin YK, Roznyatovsky VA, Zyk NV, Majouga AG, Beloglazkina EK. Petrov SA, et al. Among authors: beloglazkina ek. Molecules. 2020 Dec 8;25(24):5784. doi: 10.3390/molecules25245784. Molecules. 2020. PMID: 33302417 Free PMC article.
Dispirooxindoles Based on 2-Selenoxo-Imidazolidin-4-Ones: Synthesis, Cytotoxicity and ROS Generation Ability.
Novotortsev VK, Kukushkin ME, Tafeenko VA, Skvortsov DA, Kalinina MA, Timoshenko RV, Chmelyuk NS, Vasilyeva LA, Tarasevich BN, Gorelkin PV, Erofeev AS, Majouga AG, Zyk NV, Beloglazkina EK. Novotortsev VK, et al. Among authors: beloglazkina ek. Int J Mol Sci. 2021 Mar 5;22(5):2613. doi: 10.3390/ijms22052613. Int J Mol Sci. 2021. PMID: 33807662 Free PMC article.
69 results