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Deficiency for SAMHD1 activates MDA5 in a cGAS/STING-dependent manner.
Schumann T, Ramon SC, Schubert N, Mayo MA, Hega M, Maser KI, Ada SR, Sydow L, Hajikazemi M, Badstübner M, Müller P, Ge Y, Shakeri F, Buness A, Rupf B, Lienenklaus S, Utess B, Muhandes L, Haase M, Rupp L, Schmitz M, Gramberg T, Manel N, Hartmann G, Zillinger T, Kato H, Bauer S, Gerbaulet A, Paeschke K, Roers A, Behrendt R. Schumann T, et al. Among authors: behrendt r. J Exp Med. 2023 Jan 2;220(1):e20220829. doi: 10.1084/jem.20220829. Epub 2022 Nov 8. J Exp Med. 2023. PMID: 36346347 Free PMC article.
Microsatellite instability and loss of heterozygosity in prostatic carcinomas: comparison of primary tumors, and of corresponding recurrences after androgen-deprivation therapy and lymph-node metastases.
Rohrbach H, Haas CJ, Baretton GB, Hirschmann A, Diebold J, Behrendt RP, Löhrs U. Rohrbach H, et al. Among authors: behrendt rp. Prostate. 1999 Jun 15;40(1):20-7. doi: 10.1002/(sici)1097-0045(19990615)40:1<20::aid-pros3>3.0.co;2-4. Prostate. 1999. PMID: 10344720
Mouse SAMHD1 has antiretroviral activity and suppresses a spontaneous cell-intrinsic antiviral response.
Behrendt R, Schumann T, Gerbaulet A, Nguyen LA, Schubert N, Alexopoulou D, Berka U, Lienenklaus S, Peschke K, Gibbert K, Wittmann S, Lindemann D, Weiss S, Dahl A, Naumann R, Dittmer U, Kim B, Mueller W, Gramberg T, Roers A. Behrendt R, et al. Cell Rep. 2013 Aug 29;4(4):689-96. doi: 10.1016/j.celrep.2013.07.037. Epub 2013 Aug 22. Cell Rep. 2013. PMID: 23972988 Free PMC article.
Deregulated type I IFN response in TREX1-associated familial chilblain lupus.
Peschke K, Friebe F, Zimmermann N, Wahlicht T, Schumann T, Achleitner M, Berndt N, Luksch H, Behrendt R, Lee-Kirsch MA, Roers A, Günther C. Peschke K, et al. Among authors: behrendt r. J Invest Dermatol. 2014 May;134(5):1456-1459. doi: 10.1038/jid.2013.496. Epub 2013 Nov 22. J Invest Dermatol. 2014. PMID: 24270665 Free article. No abstract available.
Phosphorylation of murine SAMHD1 regulates its antiretroviral activity.
Wittmann S, Behrendt R, Eissmann K, Volkmann B, Thomas D, Ebert T, Cribier A, Benkirane M, Hornung V, Bouzas NF, Gramberg T. Wittmann S, et al. Among authors: behrendt r. Retrovirology. 2015 Dec 15;12:103. doi: 10.1186/s12977-015-0229-6. Retrovirology. 2015. PMID: 26667483 Free PMC article.
Loss of Trex1 in Dendritic Cells Is Sufficient To Trigger Systemic Autoimmunity.
Peschke K, Achleitner M, Frenzel K, Gerbaulet A, Ada SR, Zeller N, Lienenklaus S, Lesche M, Poulet C, Naumann R, Dahl A, Ravens U, Günther C, Müller W, Knobeloch KP, Prinz M, Roers A, Behrendt R. Peschke K, et al. Among authors: behrendt r. J Immunol. 2016 Sep 15;197(6):2157-66. doi: 10.4049/jimmunol.1600722. Epub 2016 Aug 10. J Immunol. 2016. PMID: 27511730
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