Beddoe T - Search Results

1

A T cell receptor flattens a bulged antigenic peptide presented by a major histocompatibility complex class I molecule.

Tynan FE, Reid HH, Kjer-Nielsen L, Miles JJ, Wilce MC, Kostenko L, Borg NA, Williamson NA, Beddoe T, Purcell AW, Burrows SR, McCluskey J, Rossjohn J. Tynan FE, et al. Among authors: beddoe t. Nat Immunol. 2007 Mar;8(3):268-76. doi: 10.1038/ni1432. Epub 2007 Jan 28. Nat Immunol. 2007. PMID: 17259989

2

The CDR3 regions of an immunodominant T cell receptor dictate the 'energetic landscape' of peptide-MHC recognition.

Borg NA, Ely LK, Beddoe T, Macdonald WA, Reid HH, Clements CS, Purcell AW, Kjer-Nielsen L, Miles JJ, Burrows SR, McCluskey J, Rossjohn J. Borg NA, et al. Among authors: beddoe t. Nat Immunol. 2005 Feb;6(2):171-80. doi: 10.1038/ni1155. Epub 2005 Jan 9. Nat Immunol. 2005. PMID: 15640805

3

Antagonism of antiviral and allogeneic activity of a human public CTL clonotype by a single altered peptide ligand: implications for allograft rejection.

Ely LK, Green KJ, Beddoe T, Clements CS, Miles JJ, Bottomley SP, Zernich D, Kjer-Nielsen L, Purcell AW, McCluskey J, Rossjohn J, Burrows SR. Ely LK, et al. Among authors: beddoe t. J Immunol. 2005 May 1;174(9):5593-601. doi: 10.4049/jimmunol.174.9.5593. J Immunol. 2005. PMID: 15843558

4

High resolution structures of highly bulged viral epitopes bound to major histocompatibility complex class I. Implications for T-cell receptor engagement and T-cell immunodominance.

Tynan FE, Borg NA, Miles JJ, Beddoe T, El-Hassen D, Silins SL, van Zuylen WJ, Purcell AW, Kjer-Nielsen L, McCluskey J, Burrows SR, Rossjohn J. Tynan FE, et al. Among authors: beddoe t. J Biol Chem. 2005 Jun 24;280(25):23900-9. doi: 10.1074/jbc.M503060200. Epub 2005 Apr 22. J Biol Chem. 2005. PMID: 15849183 Free article.

5

T cell receptor recognition of a 'super-bulged' major histocompatibility complex class I-bound peptide.

Tynan FE, Burrows SR, Buckle AM, Clements CS, Borg NA, Miles JJ, Beddoe T, Whisstock JC, Wilce MC, Silins SL, Burrows JM, Kjer-Nielsen L, Kostenko L, Purcell AW, McCluskey J, Rossjohn J. Tynan FE, et al. Among authors: beddoe t. Nat Immunol. 2005 Nov;6(11):1114-22. doi: 10.1038/ni1257. Epub 2005 Sep 25. Nat Immunol. 2005. PMID: 16186824

6

Structural basis for a major histocompatibility complex class Ib-restricted T cell response.

Hoare HL, Sullivan LC, Pietra G, Clements CS, Lee EJ, Ely LK, Beddoe T, Falco M, Kjer-Nielsen L, Reid HH, McCluskey J, Moretta L, Rossjohn J, Brooks AG. Hoare HL, et al. Among authors: beddoe t. Nat Immunol. 2006 Mar;7(3):256-64. doi: 10.1038/ni1312. Epub 2006 Feb 12. Nat Immunol. 2006. PMID: 16474394

7

Disparate thermodynamics governing T cell receptor-MHC-I interactions implicate extrinsic factors in guiding MHC restriction.

Ely LK, Beddoe T, Clements CS, Matthews JM, Purcell AW, Kjer-Nielsen L, McCluskey J, Rossjohn J. Ely LK, et al. Among authors: beddoe t. Proc Natl Acad Sci U S A. 2006 Apr 25;103(17):6641-6. doi: 10.1073/pnas.0600743103. Epub 2006 Apr 14. Proc Natl Acad Sci U S A. 2006. PMID: 16617112 Free PMC article.

8

Subtle changes in peptide conformation profoundly affect recognition of the non-classical MHC class I molecule HLA-E by the CD94-NKG2 natural killer cell receptors.

Hoare HL, Sullivan LC, Clements CS, Ely LK, Beddoe T, Henderson KN, Lin J, Reid HH, Brooks AG, Rossjohn J. Hoare HL, et al. Among authors: beddoe t. J Mol Biol. 2008 Apr 11;377(5):1297-303. doi: 10.1016/j.jmb.2008.01.098. Epub 2008 Feb 12. J Mol Biol. 2008. PMID: 18339401 Review.

9

Natural micropolymorphism in human leukocyte antigens provides a basis for genetic control of antigen recognition.

Archbold JK, Macdonald WA, Gras S, Ely LK, Miles JJ, Bell MJ, Brennan RM, Beddoe T, Wilce MC, Clements CS, Purcell AW, McCluskey J, Burrows SR, Rossjohn J. Archbold JK, et al. Among authors: beddoe t. J Exp Med. 2009 Jan 16;206(1):209-19. doi: 10.1084/jem.20082136. Epub 2009 Jan 12. J Exp Med. 2009. PMID: 19139173 Free PMC article.

10

Antigen ligation triggers a conformational change within the constant domain of the alphabeta T cell receptor.

Beddoe T, Chen Z, Clements CS, Ely LK, Bushell SR, Vivian JP, Kjer-Nielsen L, Pang SS, Dunstone MA, Liu YC, Macdonald WA, Perugini MA, Wilce MC, Burrows SR, Purcell AW, Tiganis T, Bottomley SP, McCluskey J, Rossjohn J. Beddoe T, et al. Immunity. 2009 Jun 19;30(6):777-88. doi: 10.1016/j.immuni.2009.03.018. Epub 2009 May 21. Immunity. 2009. PMID: 19464197 Free article.

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