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Tetrahydroindazole inhibitors of CDK2/cyclin complexes.
Lee JC, Hong KH, Becker A, Tash JS, Schönbrunn E, Georg GI. Lee JC, et al. Among authors: becker a. Eur J Med Chem. 2021 Mar 15;214:113232. doi: 10.1016/j.ejmech.2021.113232. Epub 2021 Jan 31. Eur J Med Chem. 2021. PMID: 33550184 Free PMC article.
Ligand-mediated protein degradation reveals functional conservation among sequence variants of the CUL4-type E3 ligase substrate receptor cereblon.
Akuffo AA, Alontaga AY, Metcalf R, Beatty MS, Becker A, McDaniel JM, Hesterberg RS, Goodheart WE, Gunawan S, Ayaz M, Yang Y, Karim MR, Orobello ME, Daniel K, Guida W, Yoder JA, Rajadhyaksha AM, Schönbrunn E, Lawrence HR, Lawrence NJ, Epling-Burnette PK. Akuffo AA, et al. Among authors: becker a. J Biol Chem. 2018 Apr 20;293(16):6187-6200. doi: 10.1074/jbc.M117.816868. Epub 2018 Feb 15. J Biol Chem. 2018. PMID: 29449372 Free PMC article.
Autoinhibition of MDMX by intramolecular p53 mimicry.
Chen L, Borcherds W, Wu S, Becker A, Schonbrunn E, Daughdrill GW, Chen J. Chen L, et al. Among authors: becker a. Proc Natl Acad Sci U S A. 2015 Apr 14;112(15):4624-9. doi: 10.1073/pnas.1420833112. Epub 2015 Mar 30. Proc Natl Acad Sci U S A. 2015. PMID: 25825738 Free PMC article.
3,994 results