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NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals.
Duewell P, Kono H, Rayner KJ, Sirois CM, Vladimer G, Bauernfeind FG, Abela GS, Franchi L, Nuñez G, Schnurr M, Espevik T, Lien E, Fitzgerald KA, Rock KL, Moore KJ, Wright SD, Hornung V, Latz E. Duewell P, et al. Among authors: bauernfeind fg. Nature. 2010 Apr 29;464(7293):1357-61. doi: 10.1038/nature08938. Nature. 2010. PMID: 20428172 Free PMC article.
TLR2 joins the interferon gang.
Bauernfeind F, Hornung V. Bauernfeind F, et al. Nat Immunol. 2009 Nov;10(11):1139-41. doi: 10.1038/ni1109-1139. Nat Immunol. 2009. PMID: 19841644
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