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Modifications on the Amino-3,5-dicyanopyridine Core To Obtain Multifaceted Adenosine Receptor Ligands with Antineuropathic Activity.
Betti M, Catarzi D, Varano F, Falsini M, Varani K, Vincenzi F, Pasquini S, di Cesare Mannelli L, Ghelardini C, Lucarini E, Dal Ben D, Spinaci A, Bartolucci G, Menicatti M, Colotta V. Betti M, et al. Among authors: bartolucci g. J Med Chem. 2019 Aug 8;62(15):6894-6912. doi: 10.1021/acs.jmedchem.9b00106. Epub 2019 Jul 26. J Med Chem. 2019. PMID: 31306001
Synthesis, enantioresolution, and activity profile of chiral 6-methyl-2,4-disubstituted pyridazin-3(2H)-ones as potent N-formyl peptide receptor agonists.
Cilibrizzi A, Schepetkin IA, Bartolucci G, Crocetti L, Dal Piaz V, Giovannoni MP, Graziano A, Kirpotina LN, Quinn MT, Vergelli C. Cilibrizzi A, et al. Among authors: bartolucci g. Bioorg Med Chem. 2012 Jun 15;20(12):3781-92. doi: 10.1016/j.bmc.2012.04.043. Epub 2012 Apr 27. Bioorg Med Chem. 2012. PMID: 22607879 Free PMC article.
Design, synthesis and preliminary evaluation of a series of histone deacetylase inhibitors carrying a benzodiazepine ring.
Guandalini L, Balliu M, Cellai C, Martino MV, Nebbioso A, Mercurio C, Carafa V, Bartolucci G, Dei S, Manetti D, Teodori E, Scapecchi S, Altucci L, Paoletti F, Romanelli MN. Guandalini L, et al. Among authors: bartolucci g. Eur J Med Chem. 2013 Aug;66:56-68. doi: 10.1016/j.ejmech.2013.05.017. Epub 2013 May 31. Eur J Med Chem. 2013. PMID: 23792316
Substituted piperazines as nootropic agents: 2- or 3-phenyl derivatives structurally related to the cognition-enhancer DM235.
Guandalini L, Martino MV, Di Cesare Mannelli L, Bartolucci G, Melani F, Malik R, Dei S, Floriddia E, Manetti D, Orlandi F, Teodori E, Ghelardini C, Romanelli MN. Guandalini L, et al. Among authors: bartolucci g. Bioorg Med Chem Lett. 2015 Apr 15;25(8):1700-1704. doi: 10.1016/j.bmcl.2015.03.009. Epub 2015 Mar 12. Bioorg Med Chem Lett. 2015. PMID: 25813160
336 results