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Bempedoic Acid Lowers Low-Density Lipoprotein Cholesterol and Attenuates Atherosclerosis in Low-Density Lipoprotein Receptor-Deficient (LDLR+/- and LDLR-/-) Yucatan Miniature Pigs.
Burke AC, Telford DE, Sutherland BG, Edwards JY, Sawyez CG, Barrett PHR, Newton RS, Pickering JG, Huff MW. Burke AC, et al. Among authors: barrett phr. Arterioscler Thromb Vasc Biol. 2018 May;38(5):1178-1190. doi: 10.1161/ATVBAHA.117.310676. Epub 2018 Feb 15. Arterioscler Thromb Vasc Biol. 2018. PMID: 29449335 Free article.
A novel inhibitor of oxidosqualene:lanosterol cyclase inhibits very low-density lipoprotein apolipoprotein B100 (apoB100) production and enhances low-density lipoprotein apoB100 catabolism through marked reduction in hepatic cholesterol content.
Telford DE, Lipson SM, Barrett PH, Sutherland BG, Edwards JY, Aebi JD, Dehmlow H, Morand OH, Huff MW. Telford DE, et al. Arterioscler Thromb Vasc Biol. 2005 Dec;25(12):2608-14. doi: 10.1161/01.ATV.0000189158.28455.94. Epub 2005 Oct 6. Arterioscler Thromb Vasc Biol. 2005. PMID: 16210564
198 results