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A Novel Endocrine Role for the BAT-Released Lipokine 12,13-diHOME to Mediate Cardiac Function.
Pinckard KM, Shettigar VK, Wright KR, Abay E, Baer LA, Vidal P, Dewal RS, Das D, Duarte-Sanmiguel S, Hernández-Saavedra D, Arts PJ, Lehnig AC, Bussberg V, Narain NR, Kiebish MA, Yi F, Sparks LM, Goodpaster BH, Smith SR, Pratley RE, Lewandowski ED, Raman SV, Wold LE, Gallego-Perez D, Coen PM, Ziolo MT, Stanford KI. Pinckard KM, et al. Among authors: baer la. Circulation. 2021 Jan 12;143(2):145-159. doi: 10.1161/CIRCULATIONAHA.120.049813. Epub 2020 Oct 27. Circulation. 2021. PMID: 33106031 Free PMC article.
12,13-diHOME: An Exercise-Induced Lipokine that Increases Skeletal Muscle Fatty Acid Uptake.
Stanford KI, Lynes MD, Takahashi H, Baer LA, Arts PJ, May FJ, Lehnig AC, Middelbeek RJW, Richard JJ, So K, Chen EY, Gao F, Narain NR, Distefano G, Shettigar VK, Hirshman MF, Ziolo MT, Kiebish MA, Tseng YH, Coen PM, Goodyear LJ. Stanford KI, et al. Among authors: baer la. Cell Metab. 2018 May 1;27(5):1111-1120.e3. doi: 10.1016/j.cmet.2018.03.020. Cell Metab. 2018. PMID: 29719226 Free PMC article.
Exercise-induced 3'-sialyllactose in breast milk is a critical mediator to improve metabolic health and cardiac function in mouse offspring.
Harris JE, Pinckard KM, Wright KR, Baer LA, Arts PJ, Abay E, Shettigar VK, Lehnig AC, Robertson B, Madaris K, Canova TJ, Sims C, Goodyear LJ, Andres A, Ziolo MT, Bode L, Stanford KI. Harris JE, et al. Among authors: baer la. Nat Metab. 2020 Aug;2(8):678-687. doi: 10.1038/s42255-020-0223-8. Epub 2020 Jun 29. Nat Metab. 2020. PMID: 32694823 Free PMC article.
Brown adipose tissue prevents glucose intolerance and cardiac remodeling in high-fat-fed mice after a mild myocardial infarction.
Peres Valgas da Silva C, Shettigar VK, Baer LA, Abay E, Madaris KL, Mehling MR, Hernandez-Saavedra D, Pinckard KM, Seculov NP, Ziolo MT, Stanford KI. Peres Valgas da Silva C, et al. Among authors: baer la. Int J Obes (Lond). 2022 Feb;46(2):350-358. doi: 10.1038/s41366-021-00999-9. Epub 2021 Oct 29. Int J Obes (Lond). 2022. PMID: 34716427 Free PMC article.
The cold-induced lipokine 12,13-diHOME promotes fatty acid transport into brown adipose tissue.
Lynes MD, Leiria LO, Lundh M, Bartelt A, Shamsi F, Huang TL, Takahashi H, Hirshman MF, Schlein C, Lee A, Baer LA, May FJ, Gao F, Narain NR, Chen EY, Kiebish MA, Cypess AM, Blüher M, Goodyear LJ, Hotamisligil GS, Stanford KI, Tseng YH. Lynes MD, et al. Among authors: baer la. Nat Med. 2017 May;23(5):631-637. doi: 10.1038/nm.4297. Epub 2017 Mar 27. Nat Med. 2017. PMID: 28346411 Free PMC article.
Maternal Exercise Improves the Metabolic Health of Adult Offspring.
Harris JE, Baer LA, Stanford KI. Harris JE, et al. Among authors: baer la. Trends Endocrinol Metab. 2018 Mar;29(3):164-177. doi: 10.1016/j.tem.2018.01.003. Epub 2018 Feb 3. Trends Endocrinol Metab. 2018. PMID: 29402734 Free PMC article. Review.
Phospho-ablation of cardiac sodium channel Nav1.5 mitigates susceptibility to atrial fibrillation and improves glucose homeostasis under conditions of diet-induced obesity.
Dewal RS, Greer-Short A, Lane C, Nirengi S, Manzano PA, Hernández-Saavedra D, Wright KR, Nassal D, Baer LA, Mohler PJ, Hund TJ, Stanford KI. Dewal RS, et al. Among authors: baer la. Int J Obes (Lond). 2021 Apr;45(4):795-807. doi: 10.1038/s41366-021-00742-4. Epub 2021 Jan 26. Int J Obes (Lond). 2021. PMID: 33500550 Free PMC article.
84 results