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Sex- and age-dependent genetics of longevity in a heterogeneous mouse population.
Bou Sleiman M, Roy S, Gao AW, Sadler MC, von Alvensleben GVG, Li H, Sen S, Harrison DE, Nelson JF, Strong R, Miller RA, Kutalik Z, Williams RW, Auwerx J. Bou Sleiman M, et al. Among authors: auwerx j. Science. 2022 Sep 30;377(6614):eabo3191. doi: 10.1126/science.abo3191. Epub 2022 Sep 30. Science. 2022. PMID: 36173858 Free PMC article.
Identification of the UBP1 locus as a critical blood pressure determinant using a combination of mouse and human genetics.
Koutnikova H, Laakso M, Lu L, Combe R, Paananen J, Kuulasmaa T, Kuusisto J, Häring HU, Hansen T, Pedersen O, Smith U, Hanefeld M, Williams RW, Auwerx J. Koutnikova H, et al. Among authors: auwerx j. PLoS Genet. 2009 Aug;5(8):e1000591. doi: 10.1371/journal.pgen.1000591. Epub 2009 Aug 7. PLoS Genet. 2009. PMID: 19662162 Free PMC article.
Metabolic networks of longevity.
Houtkooper RH, Williams RW, Auwerx J. Houtkooper RH, et al. Among authors: auwerx j. Cell. 2010 Jul 9;142(1):9-14. doi: 10.1016/j.cell.2010.06.029. Cell. 2010. PMID: 20603007 Free PMC article.
Mitonuclear protein imbalance as a conserved longevity mechanism.
Houtkooper RH, Mouchiroud L, Ryu D, Moullan N, Katsyuba E, Knott G, Williams RW, Auwerx J. Houtkooper RH, et al. Among authors: auwerx j. Nature. 2013 May 23;497(7450):451-7. doi: 10.1038/nature12188. Nature. 2013. PMID: 23698443 Free PMC article.
Joint mouse-human phenome-wide association to test gene function and disease risk.
Wang X, Pandey AK, Mulligan MK, Williams EG, Mozhui K, Li Z, Jovaisaite V, Quarles LD, Xiao Z, Huang J, Capra JA, Chen Z, Taylor WL, Bastarache L, Niu X, Pollard KS, Ciobanu DC, Reznik AO, Tishkov AV, Zhulin IB, Peng J, Nelson SF, Denny JC, Auwerx J, Lu L, Williams RW. Wang X, et al. Among authors: auwerx j. Nat Commun. 2016 Feb 2;7:10464. doi: 10.1038/ncomms10464. Nat Commun. 2016. PMID: 26833085 Free PMC article.
Bayesian association scan reveals loci associated with human lifespan and linked biomarkers.
McDaid AF, Joshi PK, Porcu E, Komljenovic A, Li H, Sorrentino V, Litovchenko M, Bevers RPJ, Rüeger S, Reymond A, Bochud M, Deplancke B, Williams RW, Robinson-Rechavi M, Paccaud F, Rousson V, Auwerx J, Wilson JF, Kutalik Z. McDaid AF, et al. Among authors: auwerx j. Nat Commun. 2017 Jul 27;8:15842. doi: 10.1038/ncomms15842. Nat Commun. 2017. PMID: 28748955 Free PMC article.
626 results