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Synthesis of 1,2-trans-2-acetamido-2-deoxyhomoiminosugars.
Blériot Y, Tran AT, Prencipe G, Jagadeesh Y, Auberger N, Zhu S, Gauthier C, Zhang Y, Désiré J, Adachi I, Kato A, Sollogoub M. Blériot Y, et al. Among authors: auberger n. Org Lett. 2014 Nov 7;16(21):5516-9. doi: 10.1021/ol502929h. Epub 2014 Oct 20. Org Lett. 2014. PMID: 25330462
Structural variation of the 3-acetamido-4,5,6-trihydroxyazepane iminosugar through epimerization and C-alkylation leads to low micromolar HexAB and NagZ inhibitors.
Bouquet J, Auberger N, Ashmus R, King D, Bordes A, Fontelle N, Nakagawa S, Madden Z, Proceviat C, Kato A, Désiré J, Vocadlo DJ, Blériot Y. Bouquet J, et al. Among authors: auberger n. Org Biomol Chem. 2022 Jan 19;20(3):619-629. doi: 10.1039/d1ob02280f. Org Biomol Chem. 2022. PMID: 34940771
17 results