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Unraveling Molecular Recognition of Glycan Ligands by Siglec-9 via NMR Spectroscopy and Molecular Dynamics Modeling.
ACS Chem Biol. 2024 Feb 16;19(2):483-496. doi: 10.1021/acschembio.3c00664. Epub 2024 Feb 7.
ACS Chem Biol. 2024.
PMID: 38321945
Free PMC article.
Structural insights into Siglec-15 reveal glycosylation dependency for its interaction with T cells through integrin CD11b.
Lenza MP, Egia-Mendikute L, Antoñana-Vildosola A, Soares CO, Coelho H, Corzana F, Bosch A, Manisha P, Quintana JI, Oyenarte I, Unione L, Moure MJ, Azkargorta M, Atxabal U, Sobczak K, Elortza F, Sutherland JD, Barrio R, Marcelo F, Jiménez-Barbero J, Palazon A, Ereño-Orbea J.
Lenza MP, et al. Among authors: atxabal u.
Nat Commun. 2023 Jun 13;14(1):3496. doi: 10.1038/s41467-023-39119-8.
Nat Commun. 2023.
PMID: 37311743
Free PMC article.
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Exploring multivalent carbohydrate-protein interactions by NMR.
Quintana JI, Atxabal U, Unione L, Ardá A, Jiménez-Barbero J.
Quintana JI, et al. Among authors: atxabal u.
Chem Soc Rev. 2023 Mar 6;52(5):1591-1613. doi: 10.1039/d2cs00983h.
Chem Soc Rev. 2023.
PMID: 36753338
Free PMC article.
Review.
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New Glucosamine-Based TLR4 Agonists: Design, Synthesis, Mechanism of Action, and In Vivo Activity as Vaccine Adjuvants.
Romerio A, Gotri N, Franco AR, Artusa V, Shaik MM, Pasco ST, Atxabal U, Matamoros-Recio A, Mínguez-Toral M, Zalamea JD, Franconetti A, Abrescia NGA, Jimenez-Barbero J, Anguita J, Martín-Santamaría S, Peri F.
Romerio A, et al. Among authors: atxabal u.
J Med Chem. 2023 Feb 23;66(4):3010-3029. doi: 10.1021/acs.jmedchem.2c01998. Epub 2023 Feb 2.
J Med Chem. 2023.
PMID: 36728697
Free PMC article.
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Structures of the Inhibitory Receptor Siglec-8 in Complex with a High-Affinity Sialoside Analogue and a Therapeutic Antibody.
Lenza MP, Atxabal U, Nycholat C, Oyenarte I, Franconetti A, Quintana JI, Delgado S, Núñez-Franco R, Garnica Marroquín CT, Coelho H, Unione L, Jiménez-Oses G, Marcelo F, Schubert M, Paulson JC, Jiménez-Barbero J, Ereño-Orbea J.
Lenza MP, et al. Among authors: atxabal u.
JACS Au. 2022 Dec 23;3(1):204-215. doi: 10.1021/jacsau.2c00592. eCollection 2023 Jan 23.
JACS Au. 2022.
PMID: 36711084
Free PMC article.
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Derivatives of (R)-3-(5-Furanyl)carboxamido-2-aminopropanoic Acid as Potent NMDA Receptor Glycine Site Agonists with GluN2 Subunit-Specific Activity.
Zhao F, Atxabal U, Mariottini S, Yi F, Lotti JS, Rouzbeh N, Liu N, Bunch L, Hansen KB, Clausen RP.
Zhao F, et al. Among authors: atxabal u.
J Med Chem. 2022 Jan 13;65(1):734-746. doi: 10.1021/acs.jmedchem.1c01810. Epub 2021 Dec 17.
J Med Chem. 2022.
PMID: 34918931
Free PMC article.
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Current Status on Therapeutic Molecules Targeting Siglec Receptors.
Lenza MP, Atxabal U, Oyenarte I, Jiménez-Barbero J, Ereño-Orbea J.
Lenza MP, et al. Among authors: atxabal u.
Cells. 2020 Dec 15;9(12):2691. doi: 10.3390/cells9122691.
Cells. 2020.
PMID: 33333862
Free PMC article.
Review.
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