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Peripheral opioid antagonist enhances the effect of anti-tumor drug by blocking a cell growth-suppressive pathway in vivo.
Suzuki M, Chiwaki F, Sawada Y, Ashikawa M, Aoyagi K, Fujita T, Yanagihara K, Komatsu M, Narita M, Suzuki T, Nagase H, Kushima R, Sakamoto H, Fukagawa T, Katai H, Nakagama H, Yoshida T, Uezono Y, Sasaki H. Suzuki M, et al. Among authors: ashikawa m. PLoS One. 2015 Apr 8;10(4):e0123407. doi: 10.1371/journal.pone.0123407. eCollection 2015. PLoS One. 2015. PMID: 25853862 Free PMC article.
Sensation of abdominal pain induced by peritoneal carcinomatosis is accompanied by changes in the expression of substance P and μ-opioid receptors in the spinal cord of mice.
Suzuki M, Narita M, Hasegawa M, Furuta S, Kawamata T, Ashikawa M, Miyano K, Yanagihara K, Chiwaki F, Ochiya T, Suzuki T, Matoba M, Sasaki H, Uezono Y. Suzuki M, et al. Among authors: ashikawa m. Anesthesiology. 2012 Oct;117(4):847-56. doi: 10.1097/ALN.0b013e31826a4ac8. Anesthesiology. 2012. PMID: 22913923 Free article.